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General Pathology Question Paper

General Pathology

Course:Diploma In Clinical Medicine

Institution: Meru Medical Training Centre question papers

Exam Year:2010

READ INSTRUCTIONS: PAPER CONTAINS TWO PARTS;MCQs AND ESSAY QUESTIO
NS.
1.Answer all questions
2.By guessing you lose a mark
3.Correct answer earns you a mark.

Q1.Four aspects of disease include:-
a.Cause
b.Mechanisms
c.Disharmony
d.Nature
e.Functional consequences

Q2.Disease can result from primary abnomarlities except:-
a.Genetic function
b.Pysiological function
c.Gross structural arrangement
d.Biochemical function
e.Nature of morphological changes

Q3.Pathogenesity means:-
a.Organism that cause diseases
b.Origin and development of disease
c.The capacity to produce diseases
d.Typical of a particular disease
e.Structural alterations in tissues

Q4.The mammalian cell is Eukaryotic because it has:-
a.Cell membrane
b.Defined nucleus
c.Well-defined nucleus
d.Cytoplasms
e.Lysosomes

Q5.The simple cell lacks the separate nucleus with a free genomic acid known as:-
a.Eukaryotic
b.Karyolysis
c.Karyorrhesis
d.Pyknosis
e.Prokaryotes

Q6.Cell injury occurs via two fundamentally processes:-
a.Reversible cell injury
b.Irrervisible cell injury
c.Pysiological cell injury
d.Pathological cell injury
e.All of the above

Q7.Cessation of blood flow causes:-
a.Hypoxia
b.Hypoglycaemia
c.Hyponatreamia
d.Hypokalemia
e.Hypocalcaemia

Q8.The following are effects of ATP depletion which one is NOT:-
a.Failure of calcium pump
b.Disruption of protein synthesis
c.Alteration in cellular energy metabolism
d.Mitrochondal damage
e.Accumulation of oxygen free radicals

Q9.The pattern of coagulative necrosis is associated with:-
a.Tuberclosis
b.Syphilis
c.Myocardial infarcts
d.Hypertension
e.None of the above

Q10.Physiological metabolic adaptation of cell occur in:-
a.Fasting
b.Drug administration
c.Endometrial hyperplasia
d.Lack of calcium
e.All of the above

Q11.Pathological hyperplasia include:-
a.Proliferation of glandular epithelium
b.Compensatory hyperplasia
c.Benign prostatic hyperplasia
d.All of the above
f.None of the above

Q12.Causes of atrophy are:-
a.Disuse
b.Inadequate nutrition
c.Trauma
d.Old age
e.Denervation

Q13.Gametogenesis means:-
a.Develop gametes
b.Chromosomes with martching genes
c.Development of gametes
d.Expression of gene
e.Basic unit of heredity

Q14.Genetic disorders are classified into:-
a.Simple gene
b.Chromosome
c.Multifunctional
d.Microchondrial
e.All of the above

Q15.Common autosomal ressesive inheritance disease include:-
a.Retinoblastoma
b.Marfan's syndrome
c.Wilson's disease
d.Sicle cell disease
e.Albinism

Q16.The following are chemical agens of inflammation which one is not:-
a.Acids
b.Snake bites
c.Mushroom poisoning
d.Metals
e.Electricity

Q17.Exudates can be :-
a.Seriuos
b.Liquid
c.Catarrhal
d.Purulent
e.Fibrinous

Q18.The microcirculation comprises of :-
a.Aorta
b.Inferior vena cava
c.Capillaries
d.Venules
e.Arterioles

Q19.Fluid exudates carries the following components:-
a.Interferon
b.Antibodies
c.Fibronogen
d.Phagocytes
e.Chemostatic agents

Q20.Cell derived mediators of acute inflammation include :-
a.Histamine
b.Complement system
c.Arachidomic acid derivatives
d.Kinin
e.Fibronolylic

ESSAY QUESTIONS:
Q1.Explain the cause of cell injury .

Q2.What are the benefits and harmful effects of acute inflammation.

Q3.Explain the outcome of acute inflammation.

Q4.Write brief notes on 5 main disciplines of pathology.

General Pathology Question Paper

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