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Mbio 205:Advanced Microbiology Question Paper

Mbio 205:Advanced Microbiology

Course:Medical Laboratory

Institution: Kenya Methodist University question papers

Exam Year:2013

KENYA METHODIST UNIVERSITY

END OF 2''ND ''TRIMESTER 2013 EXAMINATIONS
SCHOOL : MEDICINE & HEALTH SCIENCES
DEPARTMENT : MEDICAL LABORATORY
UNIT CODE : MBIO 205
UNIT TITLE : ADVANCED MICROBIOLOGY
TIME : 2 HOURS

Instructions:

Answer all questions in section A and B. answer one question in section C.

SECTION A

Question One

What is the O antigen of Enterobacteriaceae?

Cell surface polysaccharide
A channel controlling substance taken into the organism
A flagellar protein
A peptidoglycan matrix important for cellular rigidity
Cell wall lipopolysaccharide.

Question Two

Which of the following statements regarding enterotoxigenic E. coli is correct.

They are important causes of travelers diarrhoae
Transmission occurs from ingestion of contaminated food and water
Disease is caused by production of one or both of two types of enterotoxins
None of the above are correct
All of the above are correct

Question Three

The genera of fungi causing Tinea infections in man are

Trichophyton
Candida albicons
Epidermophyton
Microsporum
Cryptococcus neoformans

Question Four

A positive tuberculin test indicates

Protection against tuberculosis
Active tuberculosis
Previous exposure to mycobacterium
BCG vaccine not needed
BCG vaccine required.

Question Five

Viruses can be classified on the basis of

Inability of exist as extracellular parasites
Possession of capsid cellular wall
The type of nucleic acid either RNA or DNA
Their actions on living cells.
Inability to affect plants and bacteria.

Question Six

Which of the following is the modeo f action of aminoglycasides

Disruption of cytoplamsic membrane function
Inhibition of bacterial cell wall synthesis
Inhibition of bacterial DNA gyrase
Inhibition of protein synthesis
Interference with bacterial folic acid metabolism

Question Seven

Which of the following statements about herpersviruses is not true.

There are eight human herpes viruses
All are morphologically identical
All are DNA viruses
All cause vescular rash
All remain latent inside the human body after primary infection.

Question Eight

Which of the following viruses is not associated with neoplasm formation

Papilloma virus
Epstein – Barr virus
Norwalk virus
Hepatitis B virus
Human herpes type 8

Question Nine

The following statements regarding HIV are true except one

It belongs to the family retroviridae
It is an oncovirus
It is associated with the enzyme reverse transcriptase
The virus is present in all body fluids
The sexual routeis the main mode of transmission

Question Ten

The greatest number of tubercle bacilli is present in

Large sized tuberculomas
Military tuberculosis
Tuberculosis lymphadenitis
Tuberculous cavity of the lung
Ghon focus

SECTION B

Question Eleven
Draw a well labelled diagram of a virus. (5mks)

Question Twelve
List five pathogenic strains of Escherichia coli. (5mks)

Question Thirteen
Describe the bacterial cell wall. (5mks)

Question Fourteen

Enumerate four types of microscopes.

(2mks)

List six pathogenic species of Clostridium.

(3mks)

Question Fifteen
Outline he pathogenesis of dysentery. (5mks)

Question Sixteen
Briefly describe bacterial pathogenicity. (5mks)

Question Seventeen
List five methods of sterilization. (5mks)

Question Eighteen
Write short notes on bacterial endospores. (5mks)

SECTION C: Answer one question.

Question Nineteen
Write an essay on viral oncogenicity. (20mks)

Question Twenty

Discuss the pathogenesis and diagnosis of typhoid fever.

(10mks)

Discuss the actiology and treatment of pulmonary tuberculosis. (10mks)

Question Twenty One
Discuss the actiology, pathogenesis, diagnosis and treatment of histoplasmosis. (20mks)

Mbio 205:Advanced Microbiology Question Paper

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