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Hml 100: Basic Cell Biology Question Paper

Hml 100: Basic Cell Biology

Course: Bachelor Of Science In Medical Laboratory Sciences

Institution: Kenyatta University question papers

Exam Year:2010

KENYATTA UNIVERSITY
UNIVERSITY EXAMINATIONS 2009/2010
INSTITUTION BASED PROGRAMME
SUPPLEMENTARY EXAMINATION FOR THE DEGREE OF BACHELOR OF
SCIENCE (MEDICAL LABORATORY SCIENCES)
HML 100: BASIC CELL BIOLOGY

DATE: MONDAY 27TH SEPTEMBER 2010 TIME: 9.00 A.M. - 12.00 NOON
________________________________________________________________________

SECTION A: ANSWER ALL QUESTIONS 5 MARKS EACH
1
Outline the role of the plasmalemma
2
Distinguish between the roles of the smooth and rough endoplasmic reticulum
3
Draw the structure of the cell membrane

SECTION B: ANSWER ONLY ONE QUESTION 20 MARKS EACH

4
Describe blood its form and function
5
Discuss giving pros and cons the statement that “Lysosomes are suicide bags”

SECTION C: ANSWER ALL QUESTIONS IN THIS SECTION. EACH QUESTION IS
WORTH ½ A MARK

1
The section of mitochondria where electron transport and energy conversion mainly takes
place is
a)
The cristae
b)
The outer membrane
c)
The matrix
d)
The granules

2
Prokaryotes
a)
Comprise of the various types of unicellular cells
Page 1 of 7

b)
Comprise of the various typed of bacteria
c)
Have DNA in their nucleus
d)
Form colonies of independent cells

3
The lysosomal enzymes are
a)
Synthesized by the Golgi apparatus
b)
Synthesized with mannose-6 phosphate
c)
Tagged with mannose-6 phosphate in the Golgi cisternae
d)
Synthesized by the nucleus

4
Cilia and flagella are examples of
a)
Microtubules
b)
Actin
c)
Intermediate filaments
d)
microfilaments

5
The human vascular system contains about how much blood?
a)
10 – 20 liters
b)
70 – 100 liters
c)
2 – 20 liters
d)
5-6 liters

6
The hepatocyte is
a)
A multipurpose epithelial cell
b)
A multipurpose endothelial cell
c)
A specialized epithelial cell
d)
A specialized endothelial cell

7
When under stress the brain relies on
a)
Glucose from the blood
b)
Glycogen from the liver
c)
Glycogen from the brain reserves
d)
Glucose stored in the brain reserves
Page 2 of 7

8
The ribosome contains
a)
A large and small subunit with about 65% RNA and 35% protein
b)
A large and small subunit with about 10% RNA and 85% protein
c)
A groove used in amino acid synthesis
d)
A groove used to join amino acids together with carbohydrates

9
Which statement is true?
a)
Plant cells have and chloroplasts and no mitochondria
b)
Animal cells have mitochondria and no chloroplasts
c)
Bacteria have chloroplasts and no mitochondria
d)
Bacterial cells have mitochondria

10
Which statement is false about the role of the cytoskeleton
a)
To stabilize the cell and organelle shape
b)
To produce motion inside the organelles
c)
To form a interlocking three dimensional meshwork
d)
To organize the cytoplasm and organelles

11
Centrioles are examples of
a)
Microtubules
b)
Actin
c)
Intermediate filaments
d)
microfilaments

12
Bone dissolution by oesteoclasts is an example of
a)
Autophagy
b)
Metamorphosis
c)
Autolysis
d)
Heterophagy

Page 3 of 7

13
Mobilization of cell storage bodies e.g. secretary bodies is an example of
a)
Autophagy
b)
Metamorphosis
c)
Autolysis
d)
Heterophagy

14
Eukaryotes
a)
Have a membrane-enclosed nucleus
b)
Are invariably unicellular
c)
Form colonies of independent cells
d)
Are less complex than prokaryotes

15
The prokaryotic single chromosome is condensed to form
a)
The DNA
b)
The RNA
c)
The nucleoid
d)
The genome

16
The outermost layer of most prokaryotes species are surrounded by
a)
A thick polysaccharide cell wall
b)
The cell membrane
c)
A layer of slime
d)
A gelatinous protein capsule

17
The major lipid of which cell membrane is composed is
a)
Sphingomyelin
b)
Cholesterol
c)
Phospholipids
d)
Neutral lipid

18
Which of the following is not enclosed by a membrane?
a)
Plasmalemma
b)
Endoplasmic reticulum
Page 4 of 7

c)
Lysosome
d)
Golgi Apparatus

19
The specific heterochromatic body that characterizes the nucleus of the majority of
female mammalian cells and is often found near the nuclear periphery is called a:
a)
Drum stick
b)
Chromatin
c)
Nucleolus
d)
Barr body

20
During maximum muscular exercise as in a sprint, there is a large increase in glucose
consumption by skeletal muscle, most of the glucose consumed under these conditions comes
from
a)
The mitochondria
b)
The fatty tissues
c)
The liver
d)
Muscle glycogen

21
When phagocytes engulf and digest bacteria that is an example of
a)
Autophagy
b)
Metamorphosis
c)
Autolysis
d)
Heterophagy

22
The three basic forms of endoplasmic reticulum are
a)
Smooth, rough and neutral
b)
Smooth, rough and vesicles
c)
Cisternae, vesicles and tubules
d)
Vacuoles, vesicles and membranes

23
Which of the following statements is true? The rough endoplasmic reticulum..
a)
Is composed of tubules and vesicles studded with ribosomes on the outer surface
Page 5 of 7

b)
Is composed of membranes studded with ribosomes on the inner surface
c)
Is extensive in cells that synthesize proteins for use within the cell
d)
Is extensive in cells that synthesize proteins for use outside the cell, for export

24
The smooth endoplasmic reticulum is not the site for
a)
Detoxification
b)
Conduction
c)
Steroid production
d)
Modification of proteins

25
The three classes of ribosomes are:
a)
Animal, plant, organelle
b)
Bacterial, organanele, eukaryote
c)
Mitochondrial, chloroplast, bacterial
d)
Protein, RNA, DNA

26
In the Golgi Apparatus
a)
The vesicles are derived from the smooth endoplasmic reticulum
b)
The cisternae is continuous with other organelles like the endoplasmic reticulum
c)
The glycosidases and glycsyl transferases catalyse the modification of lipids
d)
There is sulphation and phosphorylation of lysosomal carbohydrates

27
Mitochondria are
a)
Very similar to gram negative bacteria
b)
Very similar to gram positive bacteria
c)
Have plate like cristae in the inner membrane
d)
Have a readily permeable inner membrane with cristae

28
The release of T3 and T4 by thyroid cells is an example of
a)
Autophagy
b)
Metamorphosis
Page 6 of 7

c)
Autolysis
d)
Heterophagy

29
Kinesin and cytoplasmic dynein are examples of
a)
Microtubules
b)
Actin
c)
Intermediate filaments
d)
Microfilaments

30
The matrix of the mitochondria contains
a)
The glycolytic pathway enzymes
b)
The elementary particles
c)
The Krebs cycle enzymes
d)
Enzymes of the electron pathway

……………………………

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Hml 100: Basic Cell Biology Question Paper

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