Get premium membership and access revision papers, questions with answers as well as video lessons.

Got a question or eager to learn? Discover limitless learning on WhatsApp now - Start Now!

Human Physilogy Paper I Question Paper

Human Physilogy Paper I

Course:Bachelor Of Science In Nursing And Public Health

Institution: Kenyatta University question papers

Exam Year:2009

KENYATTA UNIVERSITY
FIRST SEMESTER EXAMINATIONS 2009/2010
UNIVERSITY EXAMINATIONS FOR DEGREE OF BACHELOR OF SCIENCE
(NURSING AND PUBLIC HEALTH)

HNS 106: HUMAN PHYSILOGY PAPER I

DATE: Wednesday 23rd December 2009
TIME: 8.00am -10.00am

INSTRUCTIONS:

1.
Which of the following statements is not true concerning conduction of action

potential along myelinated axons?

a.
Myelin an effective insulator and current flow through it is negligible

b.
Depolarization in myelinated axons is through salutatory conduction from

one node of Ranvier to the next

c.
Myelinated axons conduct up to 50 times faster than unmyelinated axons

d.
The chemical gradient at the depolarized node serves to depolarize to a

firing level the node ahead of the action potential.

2.
All of the following statements regarding the “ALL OR NONE’ law of action

potential are true except.

a.
A threshold intensity has to be reached for an action potential to be
generated.

b.
A weak stimulus will take longer to read the threshold and generate an
action
potential
Page 1 of 8

c.
A strong stimulus will increase the amplitude of the action potential but

the number of action potential remains the same.

d.
A strong stimulus may cause increased number of action potentials by

their amplitude remains the same.

3.
Excitation contraction coupling involves all of the following except?

a.
Troponin I firmly binding actin forming troponin tropomysin complex

b.
Transmission of an action potential to all the fibrils in the muscles fibre

via the T-tubule system

c.
The release of Ca2+ from the sarcoplasmic reticulum which binds to

troponin C and initiates contraction

d.
Hydrolysis of ATP and ADP and phosphate as this process requires
energy
consumption

4.
Which of the following statements on muscles isotonic and isometric contraction

is not true?

a.
In isometric contraction no works is done

b.
In isometric contraction there is not change of overall lengths of the
contracted
muscle

c.
Isotonic contraction occurs against a constant load and with the same
tension

d.
In some situations of isotonic contraction negative work may be done

5.
All of the following statements on fluid volumes are correct except?

a.
Transcelluar fluids are special fluid sequestrations e.g cefalospinal fluid
and
synovial
fluid

b.
Interstizial fluid is the component of extracellular fluid that is not plasma
(restricted
in
the circulatory system)

c.
By using inulin the extracellular fluid volume is about 14 litres in a 70Ks

man

d.
Interstizial volume can be determined by mannitol
Page 2 of 8
6.
All of the following statements are true about serpentine receptors except?

a.
They are transmembrane proteins that traverse the membrane 7 times

b.
They transfer their ligand to the cytoplasm through conformational change

hence the ligand effects interacellualr action.

c.
They are G- proteins that mediate intracellulare action through second
messengers

d.
GTP binding of the receptor protein forms GTP-proteins complex which

brings about the effect.

7.
Which of the following is not a buffer?
(a)
HCO3-
(b)
H2PO42-
(c)
C1-
(d)
Heamoglobin
(Hb-)

8.
All the following statements are true about the mitochondria except?

a.
They are the eukaryotic cells’ principle energy generator

b.
Mitochondrial genetic material a DNA is inherited from the mother and

does not have appropriate DNA repair mechanism.

c.
Enzyme complexes for oxidative phosphorylation are found in the christae

d.
The mitochondrial DNA is solely responsible for the coding of the protein

complexes involved in oxidative phosphrylation

9.
All of the following are components of the cell membrane except?
(a)
Cholesterol
(b)
Palmytoyl
phisphatidyl
ethanolamine
(c)
Triphsphate
(IP3)

(d)
Phosphatidyl inosital diphosphate (PIP2)

Page 3 of 8

10.
Protein synthesis can occur in all the intracellular organelles except
(a)
Granular
endoplasmic
reticulum

(b)
Smooth endoplasmic reticulum
(c)
Polysomes
(d)
Mitochondria

11.
Which of the following statements is true about digitalis glycoside (digoxin) in its

action on the myocardial cells?

a.
It stabilizes the myocardial membrane by inhibiting Na+/K+ ATPase

activity thereby allowing Na+ to accumulate in the cell

b.
There is increased Na+/Ca++ antiport with 3Na+ taken in by the cell and

Ca++ expelled leading to membrane stability

c.
It is used in patients with altered heart rhythm but not heart failure because

the membrane stabilization does not increase the force of contraction of
the
myocardium

d.
It increases the functionality of Na+/K+ atpace with increased

intracellulare K+ which is responsible for the membrane stability

12.
All of the following are cell adhesive molecules (CAMs) except?
(a)
Integrins
(b)
IgG
(c)
Catherins
(d)
IgM

13.
Which of the following are well adhesive molecules (CAMs) except?

a.
In their absence cells rapture easily and blistering occurs

b.
They form spindles which move chromosomes during mitosis

c.
They transport orgnelles like Mitochondria, secratory granules and
endocytotic
vescilcles,
etc

d.
They are made of actin which is present in all human cells

Human Physilogy Paper I Question Paper

More Question Papers

Popular Exams