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Immunology Question Paper
Immunology
Course:Bachelor Of Science In Nursing And Public Health
Institution: Kenyatta University question papers
Exam Year:2009
KENYATTA UNIVERSITY
UNIVERSITY EXAMINATIONS 2009/2010
FIRST SEMESTER EXAMINATION FOR THE DEGREE OF BACHELOR OF
SCIENCE (NURSING AND PUBLIC HEALTH)
HNS 205: IMMUNOLOGY
DATE: MONDAY, 28TH DECEMBER 2009
TIME: 11.00 A.M. - 1.00 P.M.
INSTRUCTIONS: All Questions are compulsory.
SECTION A (20 MARKS)
Multiple choice questions.
Tick the single best answer.
1.
The following cell is the odd one out
(a)
Mast
cell
(b)
Basophil
(c)
Neutrophil
(d)
Monocyte
2.
Humoral immune response mechanism of immune expression was proposed by
(a)
Dr.
Jenner
(b)
Dr.
Pastuer
(c)
Dr.
Bordet
(d)
Dr.
Metchinikoff
3.
A substance that elicit and react with production of immune response is best described as
(a)
Antibody
(b)
Adjuvant
(c)
Hapteu
(d)
Antigen
Page 1 of 5
4.
Which one of the following is not true about innate immunity.
(a)
Macrophages are involved
(b)
Complement proteins are involved
(c)
Natural killer cells are involved
(d)
B cells are involved
5.
Which one of the following is not a function of red bone marrow
(a)
Production of cells of immune system
(b)
Antigen independent maturation of B cells
(c)
Antigen independent maturation of T cells
(d)
Antigen processing environment where mature lymphocytes interact with antigens
6.
Which one of the following statement is not true about IgE
(a)
Has two Epitopes binding sites
(b)
Produced in response to parasite worms
(c)
Protects the external mucosal surfaces
(d)
FC portion of IgE can activate classical complement pathways.
7.
Which one of the following statements is not true about antibodies antigenic determinants.
(a)
Antibodies to isotypic determinants can be raised by injecting antibodies from one
species
into
another.
(b)
Antibodies to allotypic determinant can be raised by injecting antibodies from one
member of the species into another member of the same species.
(c)
Antibodies to idiotypic determinants can be formed in self naturally.
(d)
Antibodies to idiotypic determinants cannot be induced in allotypically identical
member of a species.
8.
Clonal section of antibody formation was proposed by:
(a)
F. M. Burnet
(b)
Linus
Pauling
(c)
Louis
Pasteur
(d)
Paul
Elitich
Page 2 of 5
9.
Which one of the following statement is not true about concept of self and non self
discrimination.
(a)
There is discrimination between self and non self components.
(b)
There is discrimination between noxious and beneficial substances
(c)
Immune responses are proportional to the degree of foreigners
(d)
State of tolerance is maintained against foreign components
10.
Macrophages were described for the first time by
(a)
Emil von Bohring
(b)
Robert
Koch
(c)
Elie
Metchinikoff
(d)
Louis
Pasteur
11.
Peyer’s patches is best classified under
(a)
Central lymphoid organs
(b)
Tertially
lymphoid
organs
(c)
Generative lymphoid organs
(d)
Primary lymphoid organs
12.
Major histocompatibility complex class II antigens are associated with function of
(a)
T helper cells
(b)
Natural killer cells
(c)
Cytotoxic
T
cells
(d)
Neutrophils
13.
Which one of the following activity is not associated with leucocyles
(a)
Removing damaged or dead cells
(b)
Attacking
and
destroying invading organisms
(c)
Agglutination of bacteria
(d)
Neutralizing
foreign substances like toxins
Page 3 of 5
14.
One of the following is not a function of platelets
(a)
Removing damaged red blood cells.
(b)
Promoting vasoconstriction
(c)
Sealing of damaged blood vessels
(d)
Formation of fibrin
15.
Which one of the following is not true about hay fever
(a)
IgE is involved
(b)
Inflammatory reactions are involved
(c)
Involves low dose proteins
(d)
Involves highly soluble and stable proteins
16.
One of the following is not true on functional categories of cytokines
(a)
Mediators and regulators of innate immunity
(b)
Mediators and regulators of adaptive immunity
(c)
Stimulators
and
regulators of cell proliferation
(d)
Stimulators of haemopoiesis
17.
Which one of the following is not a trigger of complement activation?
(a)
Cytokine
secretions
(b)
Antigen-Antibody immune complex
(c)
Carbohydrate
component
of bacteria cell wall.
(d)
Antibody binding to cell surface.
18.
One of the following is not an activity of complement:
(a)
Inflammatory
responses
(b)
Destruction
of
pathogen or infected cells
(c)
Facilitate clearance of dead cells and immune complexes
(d)
Facilitate antibody formation
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