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Introduction To Clinical (Pharmacology) Question Paper
Introduction To Clinical (Pharmacology)
Course:Bachelor Of Science In Nursing And Public Health
Institution: Kenyatta University question papers
Exam Year:2009
KENYATTA UNIVERSITY
FIRST SEMESTER EXAMINATIONS 2009/2010
SUPPLEMENTARY/SPECIAL EDUCATION EXAMINATIONS FOR DEGREE
OF BACHELOR OF SCIENCE (NURSING AND PUBLIC HEALTH)
HNS 210: INTRODUCTION TO CLINICAL (PHARMACOLOGY)
DATE: THURSDAY 3RD DECEMBER 2009 TIME: 8.00 A.M – 10.00 AM
INSTRUCTIONS:
SECTION A
Multiple choice questions
1.
Which of the following statements is true regarding drug toxicity?
a.
Vancomycin use may lead to hypersenativity
b.
Doxycycline use may lead to rephontoxicity
c.
The rate limiting toxicity of ciprofloxacin in use in children is hepatotocity
d
The Chloraphemical use may cause a circulatory collapse adults.
2.
Which of the following agents are not absorbed form anteral route?
a.
Clindanycin
b.
Neonycin
c.
Paramomycin
d Azithromycin
3.
Which of the following statements are true regarding cephalosporins
a.
Susptability of gram positive organisms increases with newer generations.
b.
Cefadrocial is useful in treatment of urinary tract infections
Page 1 of 5
c.
Cefixime is an injectable only fourth generation agent
d
Cefriazone is excreted mainly via the liver
4.
Which of the following is not a toxicity of septrin.
a.
Kernicterus in protein baby
b.
Agranulosytesis
c.
Onychlysis
d Crystalluria
5.
The following statements are false. Which one is true?
a.
Cefuroxine is effective in treatment of meningitis
b.
perfioxacin is effective against pseudodornonas
c.
Contrimoxazole is useful for treatment of toxoplasmosis
d
Chloraphenicol is effective in treatment of ostermyelitis
6.
Which of the following drugs are useful in treatment of urinary tract infection?
a.
Doxycline
b.
Klarythroimycin
c.
Cloxacillin
d Nitofurantoin
7.
Which of the following statements about antituberculous therapy is true?
a.
Purazinamide use may lead to hepatotoxicity
b.
Ethambutol may be administered to a 3 year old child with TB adenitis
c.
The initiation phase tuberculoisis treatment in children must include
streptomycin
for
one
month
d
Slow acetylators of isoniazide tend to get hepatotoxicity.
8.
The following agents may be used to treat leprosy. Which one should not
a.
Rifanpisin
b.
Dapsone
Page 2 of 5
c.
Isoniazid
d.
Clofamizine
9.
The following are indications for uses of adrenalin. Which one is false?
a.
Asystole
b.
Hypersensitivity
reaction
c.
Bradycardia
d.
Biochoconsteiction
10.
Which of the following interactions occur at the level of elimination of the drugs
a.
Tetrycycline and Calcium tablets
b.
Antacidd and phenobarbitone
c.
Amoxil and probenecid
d Sadium
bicarbonate and Iron tablets
11.
Which of the following statements about antimalaria therapy is true?
a.
Arteinerther is both a liver and blood schizonticide
b.
Quinine use lead to black water fever
c.
Amodiaguin by be used for chemophophylasis
d Halofantrin
is
indicated for severe malaria
12.
The following agents are contraindicated in pregnancy. Which one is safe
a.
Minocycline
b.
Ciprofloxalin
c.
Chlorampherico
d Efavirenz
13.
Which one of the following statements about anti-histamines are false?
a.
Chromoglycate
prevents allergies symptoms
b.
Chlorpheniramine is a mast cell stabilizer
c.
Promethazine has sedative effects
Page 3 of 5
d
Adevenalin acts by activating antagonistic physiologic processes.
14.
Which of the following about antifungal agents are true?
a.
Ternafin may be used orally for terea capitis
b.
Gricofulvin should be daminstered orally to treat
an
empty
stomach
c.
Clotrimazole may be administered orally to treat vaginal candidiasd.
d.
Fluconazole is administered as a single stat oral dose for ora-pharyngeal
candididiasis.
15.
Which of the following statements about anti-retroviral agents is false?
a.
Abacavir use is associated with hypernsitivity reactions
b.
Navirapine ues is associated with severe anaemia
c.
Didanosive use may lead to pancreatitis
d
lopnavir use may used associated with lipdystrophy.
16.
Which of the following statements about pre-anesthetic medications are false?
a.
Diacephan serves as an anxiolytic
b.
Pethidine acts as analysic and sedative
c.
Morphine acts as an muscle relaxant
d
Atropine helps to reduce respiratory secetions
17.
Which of the following statements about anti-helminttic agents is true?
a.
Niclosanide is effective against axariasis
b.
Praziquantel is effective in treatment of scitistosomiasis
c.
Alberndazole should be given as a stat dose in hydatid diseases
d.
Piperzine is indicated for hookworm infections.
18.
Which of the following statements are false?
a.
Hyaluronidase addition to intramuscular drug improved penetration
Page 4 of 5
b.
Additional of adrenalin to lynolaine slows drug absorption.
c.
Gublingual
drug
administered escapes first pass metabolism
d
Polar drugs better absorbed from the gastro-intestinal system, then non
polar
–drugs.
19.
Which of the following statements about analygesics is false?
a.
Fentamyl is synthetic opiate
b.
Morphine is more potent than heroine as an analyesic
c.
Pethidine has some anti-tussive effect
d.
Naloxone may be administered as an antidote to diazepam poisoning
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