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Dicm 225: Pharmacology And Therpeutics Ii Question Paper
Dicm 225: Pharmacology And Therpeutics Ii
Course:Clinical Medicine And Surgery
Institution: Kenya Methodist University question papers
Exam Year:2011
KENYA METHODIST UNIVERSITY
END OF 3''RD ''TRIMESTER 2011 EXAMINATIONS
SCHOOL : MEDICINE & HEALTH SCIENCES
DEPARTMENT : CLINICAL MEDICINE & SURGERY
UNIT CODE : DICM 225
UNIT TITLE : PHARMACOLOGY & THERPEUTICS II
TIME : 3 HOURS
Instructions:
Write Your Admission No.
Attempt ALL the Questions
MCQ
Write T for True and F for False
An incorrect response results to loss of One Mark
No mark is awarded as lost for any Un attempted Questions
Question One
Thrombolytic drugs include:
Aspirin
Reteplase
Warfarin
Clopidogrel
Alteplase
Question Two
About cephalixin:
It’s a 1st generation cephalosporin
Exhibits post antibiotic effect
Only given parenterally
It’s safe in pregnancy
It’s a ß-lactam
Question Three
Patents with Ascaris lumbricoides can benefit from the following drugs.
Pentamidine
Metronidazole
Mebendazole
Sulfadiazole
Albendazole
Question Four
B1 selective antagonist include:
(a) Carvedilol
(b) Pindolol
(c) Atenolol
(d) Bisoprolol
(e) Misoprolol
Question Five
The following is true about metformin
(a) Useful in patients with hypothyroidism
(b) It’s a sulfonylurea
(c)It’s safe in pregnancy
(d) Commonly used for type II D.M
(e) Contraindicated in patients with renal failure
Question Six
Loop diuretics include
(a) Furosemide
(b) Hydrochlorotiazide
(c) Acetazolamide
(d) Torsemide
(e) Spironolactone
Question Seven
Organ level effects of benzodiazepines include:
Sedation
Gastritis
Hypnosis
Anesthesia
Anti-convulsant effects
Question Eight
Inhaled anesthetics include:
Nitrous oxide
Isoflurane
Ketamine
Propofol
Halothane
Question Nine
About Phenytoin
It’s a Na+ channel blocker
Indicated in treatment of partial seizures
It’s an antipsychotic
Can lead to congenital anomalies during pregnancy
Gingival hyperplasia is a known side effect.
Question Ten
The following drugs inhibit cell wall synthesis
Ampicillin
Ceftriaxone
Clavulanic acid
Sulbactan
Vancomycin
Question Eleven
Insulin therapy, adverse effects include:
Hypoglycaemia
Weight loss
Lipodystophy
Vomiting
Hyperlipidaemia
Question Twelve
Centrally acting symphatolytic artihypertentives
Methyldopa
Labetalol
Clonidine
Terazocin
Prazocin
Question Thirteen
Long acting B2 selective agonists used in asthma include:
Salmetorol
Salbutamol
Formoterol
Theophylline
Ipubrumium bromide
Question Fourteen
True or false:
Na+ cromolyn is a mast cell stabilizer
Na+ cromolyn is leukotriene pathway ihbibitor
Inhaled drugs are preferred to orals in Asthma
Theophylline has a narrow therapeutic window
Status asthmaticus patients can benefit from montelukast
Question Fifteen
Digoxin:
Is a cardiac glycoside
Negatively inotropic
Uses include hypertension
Useful in atrial fibrillation
Toxicity can be reversed byimmune digiband
Question Sixteen
Class II anti-rrthymic drugs include:
Digoxin
Bisoprolol
Atenolol
Sotalol
Quinidine
Question Seventeen
Stavudine drug toxities are;
Neuropathy
Lipodystophy
Lactic acidosis
Pancreatitis
All the above
Question Eighteen
Selective cox-2 inhibitors group of NSAIDS
MeloxICCM
Indomethacin
Celecoxib
Diclofenac
Ipubrofen
Question Nineteen
H. Pylori esadication can be achieved by
Clarithromycin
Tinidazole
Metronidazole
Albendazole
Pryintal pamoate
Question Twenty
Dopamine D2 – receptor blockers group of anti-emetics
Ondansetron
Granisetron
Domperidone
Chlorpromazine
Metochlopramide
SHORT ANSWER QUESTIONS
Question One
List atleast two drugs used in treatment of the following:
Hepatitis B
(2 Marks)
Herpes-simplex virus
(2 Marks)
Cytonegalovirus
(2 Marks)
Question Two
Briefly explain the mechanism of action of the following drugs:
(a) Doxycline (2 Marks)
(b) Ampicillin (2 Marks)
(c) Erythromycin (2 Marks)
Question Three
Indicate with at least two drugs, appropriate cuticonvulsants
(a) Absence seizures (2 Marks)
(b) Generalised tonic clonc seizures (2 Marks)
Question Four
Outline dermatologic vehicles (4 Marks)
Question Five
List the commonly used oral iron preparations. (4 Marks)
Question Six
With examples list classes of diuretics. (6 Marks)
Question Seven
Outline FOUR (4) calcium channel blockers (4 Marks)
Question Eight
Write short notes on Amphoterecin B (5 Marks)
Question Nine
List the clinical uses of misoprostol (3 Marks)
Question Ten
Outline the adverse effects of non steroidal anti-inflamatory agents. (4 Marks)
LONG ANSWER QUESTIONS
Question One
Write notes or drugs used in treatment of peptic ulcer disease (15 Marks)
Question Two
Write notes on oral drugs used in diabetes mellitus.
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