
Foundations of modern biotechnology (1838-1953).
? 1838, Matthias Schleiden, determined that all plant tissue was composed of cells and that each plant arose from a single cell.
? 1839, Theodor Schwann, came to a similar determination as Schleiden, for animals.
? 1858, Rudolf Virchow, concluded that all cells arise from cells and the cell is the basic unit of life.
? Before cell theory the main belief was vitalism: whole organism, not individual parts, posses life.
? By the early 1880s, microscopes, tissue preservation technology, and stains allowed scientists to better understand cell structure and function.
1952: Alfred Hershey and Martha Chase.
?Used T2 bacteriophage, a virus that infects bacteria.
?Radiolabeled the bacteriophage with S35 (Protein) and P32 (DNA).
?Bacterial cells were infected and put in a blender to remove phage particles.
?Analysis showed labeled DNA inside the bacteria and was the genetic material.
1953 watson and crick.
• Determined the structure of DNA.
• Rosalind Franklin and Maurice Wilkins provided Xray diffraction data.
• Erwin Chargaff determined the ratios of nitrogen bases in DNA.
• DNA replication model.
• DNA bases made up of purine and pyrimidine.
jim items answered the question on March 28, 2019 at 12:32
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