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1.Age
Older Persons Are Often More Sensitive to Toxic Action Than Are Younger Adults. With Aging
Comes a Diminished Reserve Capacity in the Face of Toxic Stress.
2.Health conditions-
Pre-Existing Disease or Other Medical Conditions Can Result in Greater Sensitivity to Toxic Agents. An Individual With a Pre-Existing Sensitivity to a Known Material Should Not Be Placed in a Work Environment That Might Compound the Condition.
3.Previous or Concurrent Exposures
Previous Exposure to Work Place Chemicals or Vapors Can Sometimes Result in Cumulative Effects Within the Body. In Addition, Some People Can Develop a Sensitivity to These Materials Over Time.
4.Route of exposure
Exposure through injection is the most dangerous of all the four pathways this is because the drug gets directly into contact with the blood.
5.Work place environmental factors
In Industries Such As Smelting or Steel Making, High Temperatures Are Encountered. As Well As Air Contaminants That Must Be Controlled.
6.Gender
Males and Females may respond differently to the Same Material.
7.Individual susceptibility and Genetics
Hereditary Factors Also Can Be of Importance. Genetic Defects May Render Certain Individuals More Sensitive to a Given Material.
Frederick paul answered the question on January 29, 2020 at 18:20
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