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Outline and explain the various homeostatic functions of the liver in mammals

      

Outline and explain the various homeostatic functions of the liver in mammals

  

Answers


Kavungya
Deamination
Process of removal of an amino group from an amino acid molecule; the process gets rid of
excess amino acids in the body; as the body is not able to store them; the amino group enters
the ornithine cycle; where it is combined with carbon (IV) oxide to form urea; which is
excreted in urine through the kidney;

Heat production;
Many metabolic activities take place in the liver; releasing heat energy; that is distributed by
the blood to other parts of the body; this helps in thermoregulation; Storage of vitamins and
mineral salts; Vitamins A, B, D, E and K; are stored in the liver; worn-out red blood cells, are
broken down to yield iron; which is stored in the liver in form of ferritin; this is used later in
case of shortage;

Formation of red blood cells;
Occurs in the liver of the foetus; the liver also breaks down old/exhausted red blood cells;
leading to formation of more in the bone marrow to replace the worn-out cells; to enhance
oxygen and carbon (IV) oxide distribution;

Regulation of blood sugar level;
Liver cells convert excess glucose into glycogen and fats under the influence of insulin
hormone; the stored glycogen is however converted back to glucose; when glucose levels are
low; by the liver cells; under the influence of glucagon hormone;

Regulation of plasma proteins;
Plasma proteins such as prothrombin and fibrinogen are manufactured in the liver using the
amino acids found in the liver; they play a major role in blood clotting; that prevents excessive
blood loss and infection at the injured area; other plasma proteins produced by the liver such
as serum and albumen; contribute to the
maintenance of osmotic pressure in the body; non-essential amino acids are also synthesized by
the liver; for use by the body;

Storage of blood;
The liver is highly vascularised; hence it is capable of holding a large volume of blood when the
blood vessels dilate during hot conditions; when the temperatures are low, the blood vessels
constrict under the influence of the endocrine and nervous systems; hence less blood is stored
in the liver; this contributes to thermoregulation;

Detoxification;
This is the process where harmful compounds such as drugs and poisons; are converted to less
toxic compounds in the liver; toxicity is caused by medication, drugs and microorganisms; the
toxic compounds are later excreted in urine; detoxification prevents the accumulation of toxins
in body cells; which could lead to death or malfunctioning of the body cells;
Kavungya answered the question on May 13, 2021 at 13:05


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