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Clinical Bacteriology I Question Paper

Clinical Bacteriology I 

Course:Bachelor Of Science In Medical Laboratory Science

Institution: Kenyatta University question papers

Exam Year:2009



KENYATTA UNIVERSITY
UNIVERSITY EXAMINATIONS 2009/2010
FIRST SEMESTER EXAMINATION FOR THE DEGREE OF BACHELOR OF
SCIENCE IN MEDICAL LABORATORY SCIENCES

HML 305:
CLINICAL BACTERIOLOGY I


DATE: Thursday, 24th December, 2009

TIME: 11.00 a.m. – 1.00 p.m.
------------------------------------------------------------------------------------------------------------
INSTRUCTIONS:
Section A

Answer ALL questions:
(10 marks each)



1.
a)
Differentiate between bacterial endotoxins and exotoxins (4 marks)

b)
Describe three modes by which bacteria are transmitted vertically giving
appropriate examples.




(6 marks)

2.
a)
Compare tuberculoid and lepromatous leprosy.

(5 marks)

b)
Outline the factors that influence the Widal test

(5 marks)

3. a) Differentiate
between 50% infectious dose (ID50) and 50% lethal dose
(LD50)






(2 marks)

b)
State the main characteristics that differentiate Shigellae from
Salmonellae.





(3 marks)

c)
Identify the virulence factors produced by S. aureus and their role in
pathogenesis.
(5
marks)
Page 1 of 2


Section B
Answer any TWO questions.
(20 marks each)
4.
Discuss the non specific serologic tests used in the diagnosis of syphilis.










(20 marks)

5.
a)
Outline and interpret the tuberculin skin (Mantoux) test for tuberculosis










(5 marks)

b)
Write notes on the types of Salmonella infections
(15 marks)

6.
Write notes on the clinical presentations resulting from infections with the
following bacteria:
a)
Bacillus anthracis





(10 marks)
b)
Yersinia
pestis
(10 marks)
Page 2 of 2






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