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Bmed 316: Metabolism Question Paper

Bmed 316: Metabolism

Course:Bachelor Of Science In Biomedical Science And Technology

Institution: Egerton University question papers

Exam Year:2012

SECTION A: ATTEMPT ALL QUESTIONS

1.(a) Explain the transport of activated fatty acids across the inner mitochondrial membrane. (4 Marks)
(b) describe the initiation of fatty acid biosynthesis. (6 Marks)
2. Define the term 'ketogenesis' and give its biomedical significance. (5 Marks)
3. Non-ketonic hyperglycemia is a condition resulting from aberrant protein metabolism. Explain (5 Marks)
4. Explain the biochemical basis of gout. (5 Marks)
5. Explain how low levels of adenosine deaminase (ADA) can cause severe immunodeficiency. (3 Marks)
6.(a) State the three conditions under which amino acids undergo oxidative degradation. (3 Marks)
(b) Using structural equations, explain the catabolism of serine and glycine. (6 Marks)
(c) Individuals with genetic defects in any enzyme involved in urea cycle cannot tolerate
protein-rich diets. Explain. (3 Marks)

SECTION B: ANSWER TWO QUESTIONS ONLY

7. Outline the complete oxidation of a saturated 13-C fatty acid. (15 Marks)
8.(a) State the biomedical significance of cholesterol. (2 Marks)
(b) Give an outline of cholesterol biosynthesis. (13 Marks)
9. Catabolism of some amino acids leads to formation of a certain ketone body:
a) Name the two amino acids and the ketone body formed. (3 Marks)
b) Give structural equations for the catabolism of the two amino acids named 9(a) above. (12 Marks)

Bmed 316: Metabolism Question Paper

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