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Hsci 108 : Human Physiology 1 Question Paper

Hsci 108 : Human Physiology 1

Course:Medical Health

Institution: Kenya Methodist University question papers

Exam Year:2013

Instructions:

Write your university registration number.
Attempt all questions
Section I consists of MCQs
Pick the most appropriate response

SECTION I

Question One

Depolarization during action potential involves

K+ influx
Na+ influx
Ca++ influx
Cl- influx

Question Two

Plateau phase of action potential is seen in

Smooth muscle
Cardiac muscle
Neurons
Skeletal muscle

Question Three

Hyper polarization is as a result of

K+ voltage gated channels
Na+ voltage gated channels
Cl- channels
Ungated K+ channels

Question Four

Osmosis refers to movement of

Water
Hydrogen ions
Na+
K+

Question Five

Absorption of iron occurs at

Jejunum
Stomach
Duodenum
Ileum

Question Six

Platelet half life is

7 days
20 days
120 days
30 days

Question Seven

Biconcave shape of erythrocytes

Mainly increases surface area
Promotes diapedesis
Increases the half life of the cells
Is due to loss of cell nucleus

Question Eight

The main anion in the intracellular fluid.

Cl-
HCO2-3
Proteins
Phosphate

Question Nine

Myelination in the central nervous system is done by

Olgodendrocytes
Schwann’s cells
Satellite cells
Astrocytes

Question Ten

Translations results in synthesis of

DNA
Protein
Lipids
RNA

Question Eleven

Transport in the neurons is

Retrograde
Clockwise
Anti-clockwise
Anterograde

Question Twelve

The main determinant of plasma oncotic pressure

Na+
K+
Na+/K+ atpase pulse
Plasma proteins

Question Thirteen

The main buffer in the extracellular fluid

Protein buffer system
Phosphate buffer system
Carbonic acid bicarbonate buffer
None of the above

Question Fourteen

Actions of insulin include

Glycolysis
Glyconeogenesis
Ketogenesis
Lipogenesis

Question Fifteen

Second messenger system is utilized by

Insulin
Thyroxine
Aldosterone
Cortisol

Question Sixteen

Zona glomerulosa is involved in synthesis of

Aldosterone
Cortisol
Catecholamines
Progesterone

Question Seventeen

Micelle formation is crucial in absorption of

Vitamin B12
Vitamin K
Glucose
Amino acids

Question Eighteen

Effects of the parasympathetic nervous system on the gut are

Increased motility
Decreased secretion
Contraction of sphincters
All the above

Question Nineteen

Hormones stored in the posterior pituitary include

Prolactin
Oxytocin
Luteinizing hormone
Thyroid stimulating hormone

Question Twenty

Match items in column A to those in B
Column A Column B
Protein synthesis Golgi apparatus
Post translation modification Nucleolus
Ribosomal subunit synthesis lysosomes
Lipid metabolism Mitochondria
Rough endoplasmic reticulum
Peroxisomes.

SHORT ANSWER QUESTIONS-40 MARKS

Question One
State the functions of the hormone glucagon. (5 marks)

Question Two
Describe the concept of hormone negative feedback (5 marks)

Question Three
Describe the transmission of a nerve impulse at the neuromuscular junction. (10 marks)

Question Four
Explain the starling forces with regards to filtration. (8 marks)

Question Five
With the aid of a diagram explain the extrinsic pathway of co-agulation. (8 marks)

Question Six
Describe the physiologic basis of blood groups. (4 marks)

LONG ESSAY QUESTIONS

Question One

Describe the physiology of the hepatobiliary system under the following headings.

Functional anatomy of the biliary tree

(6 marks)

Bile formation.

(4 marks)

Role of gall bladder

(4 marks)

Role of the bile in digestion and absorption.

(6 marks)

Question Two
Describe the fluid compartments in the body and highlight the main ions in each compartment. (20 marks)

Hsci 108 : Human Physiology 1 Question Paper

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