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Cmi 1204:Immunology Question Paper
Cmi 1204:Immunology
Course:Diploma In Clinical Medicine
Institution: Kampala International University question papers
Exam Year:2012
KAMPALA INTERNATIONAL UNIVERSITY
DAR ES SALAAM COLLEGE
SCHOOL OF HEALTH SCIENCES
2011/2012 UNIVERSITY EXAMINATIONS
END OF SEMEATER II EXAMINATION
COURSE PROGRAM : DIPLOMA IN CLINICAL MEDICINE
COURSE TITTLE : IMMUNOLOGY
COURSE CODE : CMI 1204
YEAR OF STUDY : FIRST YEAR
DATE : FRIDAY, 29TH JUNE, 2012
DURATION : 3 HOURS
TIME : 9:00 AM-12:00 PM
INSTRUCTIONS:
• Cellular phones are not allowed in the Examination Room
• Observe all University Regulations
• Do not answer any questions in this paper
• Answer ALL questions in SECTION A, any SEVEN in SECTION B and THREE in SECTION C.
SECTION A
Answer all questions in this section
1. What are the differences between naïve, effector and memory B and T lymphocytes? (2 marks)
2. What is hypersensitivity? (2 marks)
3. Explain how B lymphocytes recognize an antigen. ( 2 marks)
4. Define the following terms: (4 marks)
I. Allergen
II. Immunogen
III. Antigen
IV. Vaccine
5. Name the major functions of the thymus. (3 marks)
6. Give the characteristics that distinguish hematopoietic stem cells and progenitor cells. (2 marks)
7. Write on clonal selection theory explaining the specificity of antigen-antibody interaction? (3 marks)
8. List the mediators of inflammation. (2 marks)
SECTION B
Answer any SEVEN questions
9. What are the four steps in leukocyte extravasation? (5 marks)
10. Name the different types of vaccines. (5 marks)
11. Describe the basic structure of an antibody. (5 marks)
12. Explain the characteristics attributes displayed by adaptive immunity.(5 marks)
13. Mention the major functions of secondary lymphoid organs. (5 marks)
14. Briefly describe active and passive immunization. (5 marks)
15. Name the components of type I hypersensitivity reactions.(5 marks)
16. Briefly discuss on the four types of defensive barriers in innate immunity. (5 marks)
SECTION C
Answer any THREE questions
17. Discuss the mechanism of type I hypersensitivity reactions and mention four of the IgE-mediated disorders as a result of localized anaphylaxis (15 marks)
18. What are the factors that influence immunogenicity? (15 marks)
19. Describe the inflammatory process. (15 marks)
20. Describe the major differences between inactivated and attenuated vaccines and give the advantages and disadvantages of using attenuated microorganisms as vaccines. (15 marks)
21. Discuss on the functions of cells of the immune system. (15 marks)
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