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Pathology Paper 1 Question Paper
Pathology Paper 1
Course:Bachelor Of Science In Nursing And Public Health
Institution: Kenyatta University question papers
Exam Year:2009
KENYATTA UNIVERSITY
UNIVERSITY EXAMINATIONS 2009/2010
FIRST SEMESTER EXAMINATION FOR THE DEGREE OF BACHELOR OF SCIENCE
(NURSING AND PUBLIC HEALTH)
HNS 206: PATHOLOGY PAPER 1
DATE: TUESDAY, 22ND DECEMBER 2009
TIME: 11.00 A.M. - 1.00 P.M.
PART I
MCQs (Tick the correct answer)
1.
Immediate and early response to tissue injury include all except:
a)
Vasodilation
b)
Lymphocyte,
macrophage,
plasma
cell (mononuclear cell) infiltration
c)
Vascular leakage and edema
d)
Leukocyte emigration (mostly PMNs)
2. Vasodilatation
a)
Accounts for warmth and redness
b)
Opens
microvascular
beds
c)
Causes an early exudates (protein rich) into interstitium
d)
Causes increased intravascular pressure
3.
Leukocytes leave the vasculature routinely through the following sequence of events:
a)
Margination and rolling, Adhesion and transmigration, Chemotaxis and activation
b)
Adhesion and transmigration, Chemotaxis and activation, Margination and rolling
c)
Chemotaxis and activation, Margination and rolling, Adhesion and transmigration
d)
Margination and rolling, Chemotaxis and activation, Adhesion and transmigration
Page 1 of 5
4.
Once at site of injury, leukocytes:
a)
Recognize and attach
b)
Engulf (form phagocytic vacuole)
c)
Kill (degrade cells)
d)
Disintegrate
5. Cytokines
are:
a)
Usually released only in chronic inflammation
b)
Abnormal
cells
released
at the site of inflammation
c)
Chemicals that react are responsible for phagocytosis of bacteria
d)
Protein cell products that act as a message to other cells, telling them how to
behave.
6.
Possible outcome of acute inflammation include all but
a)
Complete
resolution
b)
Scarring
(fibrosis)
c)
Progression to chronic inflammation
d)
Chronic would formation
7.
Abscess formation is seen in
a)
Fungal
infection
b)
Mycobacterium
infection
c)
Viral
infection
d)
Parasitic
infection
8.
Sequence of cell cycle:
a)
G2, S, MITOSIS, G1
b)
S, G2, MITOSIS, G1
c)
GI, MITOSIS, S, G1
d)
MITOSIS, G1, G2, S
Page 2 of 5
9.
Complete cell cycle takes about
a)
1
hour
b)
24
hours
c)
9
hours
d)
10
hours
10.
Downs Syndrome is due to Non disjunction at:
a)
Trisomy
21
b)
Trisomy
22
c)
Trisomy
20
d)
Trisomy
46
11.
Reversible Adaptations to cell injury include all (reversible)
a)
Hydropic
degeneration
b)
Hypertrophy
c)
Necrosis
d)
Accumulations - hyaline, fat, etc
12. Apoptosis
is:
a)
Morphologic changes seen in dead cells within living tissue.
b)
Dissolution of dead cells by the cells own digestive enzymes. (not seen)
c)
Programmed cell death. Physiological, for cell regulation
d)
Changes in Homeostasis seen due to stimuli - Injury
13.
Sequence of necrosis
a)
Cell Death, Necrosis, Autolysis, Phagocytosis, Organization & fibrous repair
b)
Necrosis, Cell Death, Autolysis, Phagocytosis, Organization & fibrous repair
c)
Autolysis, Cell Death, Necrosis, Phagocytosis, Organization & fibrous repair
d)
Phagocytosis, Cell Death, Necrosis, Organization & fibrous repair, autolysis
Page 3 of 5
14.
False regarding neoplasms
a)
Sarcomas are mesenchymal tumors
b)
Carcinomas are epithelial tumor
c)
Chrondroma are bone tumors
d)
Teratomas arise from totipotent cells (usually gonads)
15.
Edema is due to:
a)
Decreased hydrostatic Pressure
b)
Lymphatic
Obstruction
c)
Increased Oncotic Pressure
d)
Sodium/Water
Release
16.
Match the following correctly:
a)
Hypertrophy - Number
b)
Hyperplasia
-
Size
c)
Metaplasia - Change
d)
Dysplasia
-
Invasive
17.
The following best describes the sequence in pathogenesis of a malignant process:
a)
Normal tissue, Dysplasia, Dysplasia, Invasive
b)
Normal tissue, Metaplasia, Dysplasia, Invasive
c)
Normal tissue, hyperplasia, Dysplasia, Invasive
d)
Normal tissue, Metaplasia, hypertrophy, Invasive
18. Transudate:
a)
Results from damage to the capillary wall
b)
Specific gravity > 1.012
c)
Specific gravity < 1.012
d)
Protein content > 3 g/dl
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