Vaccination Question Paper

Vaccination

Course:Bachelor Of Science

Institution: Kenyatta University question papers

Exam Year:2009

KENYATTA UNIVERSITY
UNIVERSITY EXAMINATIONS 2009/2010
FIRST SEMESTER EXAMINATION FOR THE DEGREE OF
BACHELOR OF SCIENCE

SBC 435: VACCINATION

DATE: Tuesday 29th December 2009 TIME 8.00am – 10.00am

INSTRUCTIONS
Answer all questions (10marks each)

Section A

1.
a)
Define
an
adjuvant.
[2marks]

b)
Describe the aluminum (alum) adjuvant and explain why they are
preferred
to
other
adjuvant.
[6marks]

c)
Differentiate between Freunds complete and incomplete adjuvant.

[2marks]

2.
a)
Differentiate between attenuated and inactivated vaccines. [5marks]
b)
Describe
the
oral
polio
vaccine.
[5marks]

3.
a)
What is isoimmunization? Explain its significance to immunization.

[5marks]

b)
State the advantages and disadvantages of synthetic peptide vaccines.

[5marks]
Page 1 of 2

Section B
Answer only Two questions (20 marks each)
4.
a)
Write short notes on hepatitis B vaccine.

[5marks]

b)
Discuss the following types of HIV vaccine types
i)
Recombinant
vectored
vaccines
ii)
Recombinant
sub-unit vaccines.
iii)
DNA
vaccines
and
replicons.
[9marks]

c)
List the challenges of developing an HIV vaccine.
[6marks]

5.
a)
What
is
herd
immunity?
[2marks]

b)
What factors affect herd immunity?

[6marks]

c)
Write short notes on active and passive immunity.
[12marks]

6. Discuss:
a)
Vaccines
for
special
populations.
[4marks]
b)
Toxoid
vaccines
[4marks]
c)
Vaccine
adverse/side
effects.
[12marks]

Page 2 of 2

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