Introduction To Principles Of Immunology Question Paper

Introduction To Principles Of Immunology

Course:Bachelor Of Science In Environmental Health

Institution: Kenyatta University question papers

Exam Year:2009

KENYATTA UNIVERSITY
UNIVERSITY EXAMINATIONS 2008/2009
SECOND SEMESTER EXAMINATION FOR THE DEGREE OF BACHELOR
OF SCIENCE (ENVIRONMENTAL HEALTH)
HEH 110: INTRODUCTION TO PRINCIPLES OF IMMUNOLOGY
DATE: Monday 24th August, 2009 TIME: 2.00 a.m. – 4.00 p.m.

SECTION 1
Answer ALL questions (20 marks).
Q1.
Compare and contrast specific immunity and non specific immunity.

[5 marks]
Q2.
Explain the difference between primary and secondary antibody responses.

[5 marks]
Q3.
Define the following terms (i) antigen
(ii)
haptens
[5 marks]

Q4.
Define an adjuvant, its mode of action and state two commonly used examples.

[5 marks]
SECTION 2 – Part I (COMPULSORY) – 20 Marks
Q5.
a)
Explain the basic structure of immunoglobulins.

[5 marks]
b)
State the immunological classes, their physical and biological functions.
[15 marks]
SECTION 2 – Part II – (Answer any 2 questions. Total = 30 marks)
Q6.
Explain three ways in which micro-organisms can avoid being killed by a
phagocytic
cell. [15
marks]
Q7. Explain
the
classification of hyper sensitivity. [15
marks]
Q8. a) Explain
the
principle of sandwich enzyme linked immunosorbent assay
(ELISA) and state its use.

[10 marks]
b)
Explain how B and T lymphocytes can be distinguished in the laboratory.
[5 marks]
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