Human Physiology Paper Ii Question Paper

Human Physiology Paper Ii

Course:Bachelor Of Science In Nursing And Public Health

Institution: Kenyatta University question papers

Exam Year:2009

KENYATTA UNIVERSITY
UNIVERSITY EXAMINATIONS 2009/2010
FIRST SEMESTER EXAMINATION FOR THE DEGREE OF BACHELOR OF
SCIENCE (NURSING)

HNS 104 (N): HUMAN PHYSIOLOGY PAPER II

DATE: Tuesday, 22nd December, 2009

TIME: 8.00 a.m. – 10.00 a.m.
------------------------------------------------------------------------------------------------------------
INSTRUCTIONS:

1.
Which of the following statements regarding the difference between Red and
Yellow marrow is not true?

a)
In the adult the vertebra and sternum have red marrow while the tibia and
femur have yellow marrow

b)
In the red marrow 75% of the cells are myeloid line progenitors while
25% are erythrocyte progenitors yet red blood cells are 500 times more
because white blood cells have a shorter life span of hours compared to a
lifespan of red cells of about 100 days

c)
Red marrow is filled with actively generating red blood cell line yet
yellow marrow is infiltrated with actively generating while blood cell line

d)
Hematopoietic stem cells are capable of replacing all cells of blood
including Kupffer cells, Dendritic cells and Langerhans cells.

2.
Each of the following is a match between the progenitor and the mature cell.
Which matching is not correct?

a)
Committed stem cell – Neutrophil
Page 1 of 7

b)
Megacaryocytes – Platelets
c)
Reticulocytes – erythrocyte
d)
Bone marrow lymphocyte precursor – T lymphocytes

3.
All of these are a matching between the circulating cell and its activated tissue
counterpart. Which matching is not correct?
a)
Monocytes – Osteoclasts
b)
B lymphocytes – Plasma cells
c)
T lymphocytes – Cytotoxic cells
d)
Monocytes – Mast cells

4.
All of the following events are observed in activated neutrophils except?
a)
Selectins attract them to the endothelial cell surface
b)
They do not bind adhesion molecules as they are transit
c)
Many are lost from the body in the Gastrointestinal tract
d)
The leave the vaxculature through the process of diapedesis

5.
All of the following are plasma proteins except?
a)
Globulin
b)
Actin
c)
Fibrinogen
d)
Albumin

6.
All of the following statements on the complement system are true except?

a)
They are plasma enzymes that aid in the cell killing effects of innate and
acquired immunity

b)
The proteins produced by these pathways help kill invading organisms by
chemotaxis, opsonization, and cell lysis
c)
they play no role in apoptosis (cell suicide)
d)
Three different pathways of enzyme cascade; the classic, alternative and
mannose binding lectin are involved.

Page 2 of 7

7.
All of the following cells mediate innate immunity except?
a)
Granulocyte neutrophils
b)
Natural killer lymphocytes
c)
T lymphocytes
d)
Macrophages

8.
Which of the following is not a precursor organ for lymphocyte generation?
a)
Lymph nodes
b)
The thymus
c)
The bone marrow
d)
The liver in fetal life

9.
Which of the following cells does not produce immune globulins?
a)
Mast cells
b)
Plasma cells
c)
B lymphocytes
d)
None of the above

10.
Autoimmune disease are caused by the failure of elimination of antibodies against
self-antigens. All of the following are examples of autoimmune diseases except?
a)
Type I diabetes mellitus
b)
Myasthenia gravis
c)
Multiple sclerosis
d)
Gauchers disease

11.
Which of the following immune-globulins is secretory?
a)
IgG
b)
IgA
c)
IgM
d)
IgE

Page 3 of 7

12.
Which of the following statements regarding plasma is not true?

a)
The capillary walls are relatively impermeable to plasma proteins hence
produce a pressure gradient
b)
The oncotic pressure of plasma proteins is about 25mmHg
c)
The difference between plasma and serum is that serum is devoid of
fibrinogen and clotting factors II V and VIII
d)
Plasma is devoid of all cellular components including platelets

13.
Which of the following myocardial electrical activities is not compatible with
life?
a)
Atrial flutter
b)
Atrial fibrillation
c)
Ventricular fibrillation
d)
Ventricular tachicardia

14.
Which of the following great vessels and connected chambers of the heart does
not contain oxygenated blood?
a)
Pulmonary artery
b)
Ascending aorta
c)
Pulmonary vein
d)
Left atria

15.
Which of the following statements concerning cardiac output is not true?
a)
Cardiac output is the product of stroke volume and heart rate
b)
Cardiac output is about 5 litres per minute
c)
Cardiac output can be determined using the thermo-dilution technique
d)
Cardiac output has little value in the determining the functionality of the
heart

16.
All of the following have a positive influence on the myocardial contractility
except?
a)
Increased blood volume in the ventricles at the end of diastole

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