Pathology - Part 1 Question Paper

Pathology - Part 1

Course:Bachelor Of Science In Nursing And Public Health

Institution: Kenyatta University question papers

Exam Year:2009

KENYATTA UNIVERSITY
UNIVERSITY EXAMINATIONS 2008/2009
SUPPLEMENTARY/SPECIAL EXAMINATION FOR THE DEGREE OF
BACHELOR OF SCIENCE (NURSING)

HNS 206:
PATHOLOGY - PART 1

DATE: Thursday, 3rd December, 2009

TIME: 8.00 a.m. – 10.00 a.m.
------------------------------------------------------------------------------------------------------------
PART A
INSTRUCTIONS:
Attempt ALL questions. Encircle the correct response.
1.
By which one of the following mechanisms are dead organelles removed from the
cell?
a)
Autophagy
b)
Hetrophagy
c)
Phagocytosis
d)
Regurgitation

2. Stable
cells
a)
Are continuously proliferating
b)
Are cells that cannot replicate under stimuli
c)
Are found mainly lining the gastric epithelium
d)
A cells that constitute parachyma of glandular organs

Page 1 of 5

3.
Which one of the following is not an adaptive cellular response?
a)
Atrophy
b)
Hypertrophy
c)
Necrosis
d)
Meta plasia

4.
Which one of the following is an opsin
a)
C3b
b)
Histamine
c)
Bacterial products
d)
C5a

5.
Which of the following cells does not participate in body’s defense through
endocytosis
a)
Monocycles
b)
Neutrophils
c)
Mast cells
d)
Macrophages

6.
Which of the following statement is Not true of oedema.
a)
It is excessive accumulation of fluid extra vascular tissues.
b)
It may be localized
c)
Is caused by increase in intra vascular osmotic pressure
d)
Accumulation may involve body cavities.

7.
The best criteria that differentiates benign from malignant tumor is
a)
Rate of growth
b)
Metastasis
c)
Invasion
d)
Metaplasia

Page 2 of 5

8.
Which one of the following is not a feature of irreversible cell injury.
a)
Hydropic change
b)
Nuclear Pyknosis
c)
Nuclear karyolysis
d)
Leakage of Lysosomal enzymes

9.
Which one of the following agents is not a chemotoctic agent
a)
Histamine
b)
Leukotriene B4
c)
Cytokine TNF
d)
Bacterial products

10.
Which one of the following enzyme is involved in metabolism of carbon
tetrachloride
a)
Cytochrome P-450 mixed oxidase
b)
Catalase
c)
Superoxide dismutase
d)
Glutathione peroxidase
Question 11 – 15
Select the best from LIST A that matches the statement in B

A
1. Lipofuscin
2. Metaplasia
3. Atrophy
4. Hydropic
change
5. Melanin
6. Dysplasia
7. Chemotaxis
8. Hypertrophy
9. Hyperplasia
10. Neuplasm
Page 3 of 5

B
11.
( ) Wear and tear pigment

12.
( ) Increase in size of a cell due to increased structural component

13.
( ) Change in one adult cell type to another adult cell type

14.
( ) Unidirectional migration of leukocytes toward target

15.
( ) Increase in cell size due to accumulation of intracellular fluid

Question 16 – 18
The fates of a thrombus are likely to be
16. A
__________________________

17. B
__________________________

18 C
__________________________

19.
_________________ is the commonest source of systemic embolism.

20.
_________________ is an area of ischaemic necrosis within tissue/organ
produced by occlusion of arterial blood supply.

PART B
1.
Explain the terms metaplasia and
hyperplasia (8
marks)

2.
Describe dystrophic and metastatic
calcifications

(8
marks)

3.
Explain the terms Autophagy and Hetrophagy

(8 marks)

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