Get premium membership and access revision papers, questions with answers as well as video lessons.

Got a question or eager to learn? Discover limitless learning on WhatsApp now - Start Now!

04-A:Histology Question Paper

04-A:Histology

Course:

Institution: Kenya Medical Training College question papers

Exam Year:2012

SECTION
I:(MCQ 40 MARKS)
1.Selective visualization of birefringent structures is best achieved
through:
a)Polarizing microscope
b)Phase contrast microscope
c)Light microscope
d)Electron microscope
e)Fluorescence microscope
2.Mechanisms of cell injury include:
a)Haemostasis
b)Adenosine triphosphate depletion
c)Increased permeability
d)Oxidative stress
e)Damage to mitochondria
3.Reversible replacement of one differentiated cell type with another
cell type is referred to as:
a)Hyperplasia
b)Atrophy
c)Dysplasia
d)Metaplasia
e)Hypertrophy
4.New growth produced by neoplasia is called?
a)Benign
b)Cancer
c)Malignant
d)Neoplasm
e)Dysplasia
5.Inflammation can be classified into:-
a)Chemical inflammation
b)Acute inflammation
c)Physical inflammation
d)Toxic inflammation
e)Chronic inflammation
6.A micro-anatomical fixative is a solution which fixes:
a)Specific nuclear substances
b)Specific elements of the cytoplasm
c)The cell cytoplasm
d)The general structures in tissues
e)Only the cell outline
7.The purpose of adding urea to nitric acid used during de-calcification
is to:
a)Increase the refractive index
b)Make the tissue soft
c)Prevent explosion of the acid
d)Dilute the acid
e)Prevent the yellow colour formation
8.Freeze drying may be applied for:
a)Bone tissue
b)Enzyme histochemistry
c)Lung tissue
d)Blood tissue
e)Tissue to be embedded using water soluble waxes:
9.Tissues shrink and become brittle when left for long in most clearing
agents,to reduce these effects the most appropriate agent(s) to use
is/are:
a)Benzene
b)Carbon tetrachloride
c)Aniline oil
d)Cedar wood oil
e)Ligroin
10.Which of the following impregnation technique is recommended for bone
tissue?
a)Use of water soluble waxes
b)Double impregnation using celloidin and paraffin wax
c)Freezing substitution method
d)Manual impregnation
e)Vacuum impregnation
11.In enzyme histochemistry,the embedding media of choice would be:
a)Water soluble waxes
b)Ester waxes
c)Paraffin waxes
d)Celloidin
e)Gelatin
12.Which of the following would lead to sections clinging to the knife
edge?
a)Blocks being too hard
b)Knife''s angle of tilt being too vertical
c)Sections being too thin
d)Sections being too thick
e)Presence of pink disease artefacts
13.The purpose of stropping a knife''s cutting edge is:
a)Refine the bevel
b)Remove knicks
c)Clean the non-cutting edge
d)Minimize the knife''s serrations
e)Create a cutting edge
14.Ribbon curling upward during sectioning is associated with:
a)Block edge parallel to one another
b)Too slow rate of cutting
c)Knife tilt is too great
d)Wax used is too soft
e)Loose block holder
15.The type of staining that does not require differentiation is known
as:
a)Metallic impregnation
b)Elective solubility
c)Progressive staining
d)Histo-chemical staining
e)Regressive staining
16.The following agent(s) can be used to solidify aqueous mountants:
a)Gelatin
b)Gum arabic
c)Glycerol
d)Phenol crystals
e)Plasticin
17.The nuclear haematoxylin stains below require that mordants and
stains are stored separately:
a)Verhoeff''s haemotoxylin
b)Weigher''s haematoxylin
c)Orcein haematoxylin
d)Harris haematoxylin
e)Mayer''s haematoxylin
18.Staining variations of tissue structures may be due to:
a)Age of the stain
b)Toxicity of the stain
c)Poor stain storage containers
d)Unlabelled stains
e)Staining time
19.Post fixation is effective after treating the tissue with:
a)Copper sulphate solution
b)A mordant
c)A bleaching agent
d)A flat solvent
e)A reducing agent
20.The following pigments can occur in tissue as a result of metabolism
except:
a)Haemazoin
b)Bilirubin
c)Porphyrins
d)Lipofuscin
e)Asbestos
21.Which of the following agents can be used to remove pink disease
artefacts?
a)Running tap water
b)20% nitric acid
c)2% nitric acid
d)70% alcohol
e)0.2% urea
22.Tissues fixed in non-alcoholic picric acid based fixative:
a)Should be washed in 20-40% alcohol
b)Should be transferred to 90% alcohol before processing
c)Form insoluble green precipitate in water
d)Require post-chroming and mordanting
e)Should not be cleared in chloroform
23.The purpose of embalming include the following except;
a)Disinfection
b)Body disposal
c)Preservation
d)Restoration
e)Colouration
24.Kaiser Ling solution II is recommended for museum specimen because
of:
a)Its ability to mix with paraffin wax
b)High concentration of formaldehyde
c)Vapour production
d)Its ability to distort tissue structures
e)Its ability to restore natural colour
25.Cytology can be applied in:
a)Embalming in histology
b)Determining the quality of microscopists
c)Enabling proper embedding of cells
d)Enabling proper embedding of cells
e)Assessing the degree of pathologist''s confidence
26.Characteristics of cancer cells include:
a)Hypo-segmentation
b)Diminished cell size
c)Loss of cell nuclear inclusion
d)Anisonucleosis
e)Hypochromasia
27.Pap smears that show inflammatory cells only are classified as?
a)CIN 0
b)CIN II
c)CIN I
d)CIN III
e)CIN IV
28.Fixation of cytological smears is best done by use of:
a)Alcohol/Ether mixture
b)95% ethyl alcohol
c)Mercuric chloride
d)10% formalin
e)Osmium tetroxide
29.Ciliated epithelium cells are found in:
a)Heart
b)Fallopian tubes
c)Kidney
d)Nostrils
e)Urethra
30.Which of the following is/are the renal functional units?
a)Kidney
b)Medulla
c)Cortex
d)Bowman''s capsule
e)Nephron
31.Tissue elastic fibres can be demonstrated by:
a)Haematoxylin and Eosin method
b)Metallic impregnation
c)Verhoeff''s haematoxylin
d)Perl''s Prussian blue
e)Weighert''s haematoxylin
32.Microscopic identification of a liver tissue is based on the
following structure(s):
a)Central vein
b)Air sacs
c)Presence of carbon pigment
d)Micro villi
e)Hexagonal tubes
33.Cytological specimens include:
a)Blood
b)Stool
c)Urine
d)Peritoneal fluid
e)Eye
SECTION II (60 marks)
1.Discuss the main types of staining processes (20 marks)
2.a)Tabulate differences between chatters and scores (10 marks)
b)Outline the steps taken to obtain a tissue after sectioning (10
marks)
3.a)Explain five factors that would lead to sections detaching from
slides.
b)Discuss factors considered when assessing malignant cells in a pap
smear.
c)Distinguish between benign and malignant tumours.
d)Explain ''ringing'' media in histology.
(20 marks)

04-A:Histology Question Paper

More Question Papers

Popular Exams