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Dcmp 128: Medical Microbiology Question Paper
Dcmp 128: Medical Microbiology
Course:Clinical Medicine & Surgery
Institution: Kenya Methodist University question papers
Exam Year:2011
KENYA METHODIST UNIVERSITY
END OF 3''RD ''TRIMESTER 2011 EXAMINATIONS
SCHOOL : MEDICINE & HEALTH SCIENCES
DEPARTMENT : CLINICAL MEDICINE & SURGERY
UNIT CODE : DCMP 128
UNIT TITLE : MEDICAL MICROBIOLOGY
TIME : 2 HOURS
Instructions: Answer ALL Questions.
SECTION A
Question One
Which of the following is not fungal related?
Cryptococcus neoformans
Candida albicans
Tinea Nigra
Chlamydiae
Coccidioides Immitis
Question Two
Which of the following is mismatched?
Bacteriostatic = Kills vegetative bacterial cells
Germicide = kills microbes
Vivicide = inactivates viruses
Sporicide = kills bacterial endospores & fungal spores
Fungicide = kills yeasts and moulds
Question Three
Which of the following is not used to classify viruses
Presence or absence of envelop
Shape of capsid
Type of nucleic acid
Host range
Biochemical reactions
Question Four
The effects of bacterial endotoxins include:
Inhibition of platelet aggregation
Inhibition of Hagerman factor
Release of interlevikin 1
Initial leucopenia
Activation of alternative complement pathway
Question Five
A characteristics that allows microorganisms to cause disease include a (n)
Virulence factor
Pathogenicity factor
Plasmid
Inclusion
Antibiotic resistance factor
Question Six
Which of the following may be used for attachment of bacterial cells to surfaces and to other cells?
Fimbraiae
Cell membrane
Glycocalyx
Capsid
Flagella
Question Seven
The following is not a mechanism of transfer of DNA between bacteria
Transduction
Sporulation
Transformation
Translation
Conjugation
Question Eight
Micro-organism that cause latent infections include
Mycobacterium tuberculosis
Varozella – zoster virus
Cytomegalovirus (cmv)
Hepatitis A
Chlamydia Trachomatis
Question Nine
Viral infections with oncogenic properties in humans include
Measles virus
Hepatitis B Virus
Paporavirus
Epstein – Barr virus
Cytomegalovirus
Question Ten
The mechanism by which enveloped viruses leave an infected host cell is called?
(a) Transduction
(b) Teratogenesis
(c) Lysogency
(d) Penetration
Question Eleven
The following is FALSE about viral pathogenesis
Viral infections spread in the body through different routes e.g blood, saliva.
Humoral immunity acts against viruses and not cell mediated immunity
Inclusion bodies produced by viruses can be single or many
In cytocidal infection, cells usually die.
Several RNA viruses can cause persistent infection.
Question Twelve
The following is FALSE about viral properties
The viral envelope contain lipoprotein
Viruses can replicate in non-living media
Viruses have no ribosome
Contain either RNA or DNA
Question Thirteen
The following is FALSE about poliovirus
Two vaccines are available
There is no vaccine for polio
Can be isolated from throat swab or stool
Sub-clinical infections are common
Three serotypes exist
Question Fourteen
Which of the following is TRUE regarding HCV and HBV
(a) HBV is dsRNA virus
(b) HCV is ssRNA virus
(c) Both viruses can grow in cell culture
(d) HBV has no chronic complication
(e) Hermodialysis but not hemophiliacs are tat risk for HCV
Question Fifteen
The following statement is FALSE about herpes viruses
There are eight human herpes viruses
All are morphologically identical
All are DNA viruses
All cause vesicular rash
All remain latent inside the human body after primary infection
Question Sixteen
The following can be used to identify staphyloccus arreurs
Identification of lancefield groups through serology
Phosphate positivity
Coagulase positivity
Fermentation of mannitol
Golden appearance of ccolories
Question Seventeen
Organism that grow in temperatures above 50oC are called
Mesophiles
Thermophiles
Psychrophiles
Halophiles
Barophiles
Question Eighteen
Nutrient agar is an example of a
Selective medium
Synthetic medium
Tissue culture medium
Complex medium
Transport medium
Question Nineteen
Which part of human urogenital tract is free of normal flora?
Vagina
Bladder
Urethra
Cervix
Vulva
Question Twenty
What is the purpose of a condenser on a light microscope?
Allows viewer to change light intensity
Concentrates the light beans on the specimen
Moves the microscope slide
Focuses the image magnified by the objective lens
Magnifies the microscope slide
SECTION B
Question Twenty One
Outline the steps taken to establish the viral etiology in the laboratory.
(5 Marks)
Question Twenty Two
Outline the laboratory diagnosis of bacterial diarrhea. (5 Marks)
Question Twenty Three
Discuss the prophylaxis of viral hepatitis. (5 Marks)
Question Twenty Four
Describe the various causes of dysentery in the tropics. (5 Marks)
Question Twenty Five
Outline the pathogenesis of Bacillus anthracis in human infections.
(5 Marks)
Question Twenty Six
Describe the laboratory diagnosis of pulmonary tuberculosis. (5 Marks)
[Question Twenty Seven
What is drug resistance
(1 Mark)
Describe type of drug resistance
(4 Marks)
Question Twenty Eight
Describe the diagnosis of cerebrospinal fever. (5 Marks)
Question Twenty Nine
Enumerate various pathogenic clostridice.
(3 Marks)
State TWO examples of non-fimibrial bacterial adhesions.
(2 Marks)
Question Thirty
Outline mutation and various types of mutation. (2 Marks)
SECTION C
Question Thirty One
Discuss bacterial colonization and invasion. (20 Marks)
Question Thirty Two
Discuss the etiology, pathogenesis, diagnosis and prophylaxis of typhoid fever.
(20 Marks)
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