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Dcmp 121: General Pathology Question Paper
Dcmp 121: General Pathology
Course:Clinical Medicine, Surgery & Community
Institution: Kenya Methodist University question papers
Exam Year:2012
KENYA METHODIST UNIVERSITY
END OF 2''ND ''TRIMESTER 2012(DAY) EXAMINATIONS
SCHOOL : MEDICINE & HEALTH SCIENCES
DEPARTMENT : CLINICAL MEDICINE, SURGERY & COMMUNITY
HEALTH
UNIT CODE : DCMP 121
UNIT TITLE : GENERAL PATHOLOGY
TIME : 3HOURS
INSTRUCTIONS: Answer ALL Questions in Section A and B and ONE Question in Section C
SECTION A
QUESTION ONE
Features of acute inflammation include:
A. Vasoconstriction of blood vessels
B. Elevated temperatures
C. Swelling
D. Reduced permeability of the blood vessels.
E. Pain.
QUESTION TWO
Examples of type 2 hypersensitivity reactions include:
A. ABO blood reactions
B. Asthma
C. Allergic rhinitis
D. Systemic lupus Erythematosis.
E. Allergic conjunctivitis.
QUESTION THREE
Viruses associated with malignancies include:
A. Human herpes virus type 8
B. Epstein Barr virus
C. Measles virus
D. Hepatitis A virus
E. Parainfluenza virus
QUESTION FOUR
Vitamin K dependent clotting factors include:
A. Factor 8
B. Factor 12
C. Prothrombin
D. Factor 7
E. Factor 9
QUESTION FIVE
Features of the Virchow`s triad include:
A. Blood stasis
B. Hyper-coagulability
C. Endothelial damage.
D. Hypertension
E. Hypoglycaemia.
QUESTION SIX
Cells involved in chronic inflammation include:
A. Macrophages
B. Neutrophils
C. Mast cells.
D. Monocytes
E. Lymphocytes
QUESTION SEVEN
Features of down`s syndrome include:
A. Trisomy 18
B. Lowset ears
C. Increased risk of cardiovascular anomalies
D. Not compartible with life.
E. Plominent epicanteral fold
QUESTION EIGHT
Exudates
A. Associated with malgnancies
B. Have a low protein content.
C. Associated with high amounts of polymorphonuclear cells
D. Common cause is hepatic failure.
E. May arise due to infections.
QUESTION NINE
Causes of bleeding disorders include:
A. Liver failure
B. Aplastic anaemia.
C. Thrombocytopeuria
D. Carebro vascular accident.
E. Iron deficiency.
QUESTION TEN
Examples of permanent cells include:
A. Epithelial cells.
B. Smooth muscles
C. Cardial muscles
D. Hepatocytes
E. Neurous
QUESTION ELEVEN
Concerning the arachidonil acid metabolites:
A. Leucotrines are associated with bronchospasms
B. Non steroidal anti-inflammatory drugs (NSAID`s) are inhibitors of
Cyclooxygenase (COX).
C. Prostaglandins are associated with fever.
D. Sterioids are potent archidonic acid pathway blockers.
E. All the above are true.
QUESTION TWELVE
Mast cells:
A. Play a major role in type 3 hypersensitivity reactions
B. Are potent vasoconstrictors
C. Contain no granules in their cytoplasm
D. When in tissues they are referred as macrophages
E. All the above are false.
QUESTION THIRTEEN
Factors considered in staging a turmor include:
A. Size of tumor
B. Histological features
C. Presence of distant metastasis
D. Lympliatic involvement
E. Rate of differentiation.
QUESTION FOURTEEN
Functions of antibodies include:
A. Opsonization
B. Neutralization of toxins
C. Phagocytosis
D. Cytolysis
E. Are produced by plasma cells
QUESTION FIFTEEN
Causes of reduced oncotic pressure include:
A. Acute glomenlonepuritis
B. Nephrotic synchone
C. Liver failure
D. Hypertension
E. Protein Energy malnutation.
QUESTION SIXTEEN
Complications of smoking include:
A. Reduced incidence of myocardial infavition
B. Associated with infertility
C. Main risk factor in developing hepatocellular carcinoma
D. Acute gastritis
E. Potent cause of hypoglycaemia.
QUESTION SEVENTEEN
Examples of lifestyle diseases include:
A. Hypertension
B. Malaria
C. Myocardial infection
D. Diabetes mellitus
E. Pulmonary tuberculosis.
QUESTION EIGHTEEN
Pathological factors associated with congenital malformations include:
A. Diabetes mellitus
B. Alcohol consumption in pregnancy
C. Toxoplasmosis
D. Syphillis
E. Exposure to ultrasound waves in early pregnancy.
QUESTION NINETEEN
Benign tumours include:
A. Lipoma
B. Hepato cellular carcinoura
C. Pappilomias
D. Sarcoma
E. Neuroblastomia.
QUESTION TWENTY
Drugs used in management of Type 1 hypersensitivity reactions include:
A. Steroids
B. Antibiotics
C. Antihistamines
D. Mast cell stabilizers
E. Beta adrenergic receptor blockers
SECTION B
QUESTION ONE
Briefly outline the features of type 1 hypersensitivity reactions. (5marks)
QUESTION TWO
Define the following terms:
Auto-graft
Syngenic graft
Xenograft
Allograft
(5marks)
QUESTION THREE
List FIVE examples of autoimmune diseases. (5marks)
QUESTION FOUR
List down the features of a wound that heals by primary intention. (5marks)
QUESTION FIVE
Briefly discuss systematic factors associated with wound healing. (5marks)
QUESTION SIX
List the features of malignant tumours. (5marks)
QUESTION SEVEN
Define the term EMBOLISM and TROMBUS. (5marks)
QUESTION EIGHT
List FIVE factors associated with development of childhood diseases. (5marks)
QUESTION NINE
List FIVE causes of cellular injury. (5marks)
QUESTION TEN
Define the term HYPERTROPHY and give examples of cells undergoing hypertrophy. (5marks)
QUESTION ELEVEN
List FIVE different types of microorganisms that are associated with infections.
(5marks)
QUESTION TWELVE
List FIVE causes of immune-supression. (5marks)
SECTION C
QUESTION ONE
a) Discuss the process of acute inflammation. (15marks)
b) Discuss the differences between acute and chronic inflammation.
(10marks)
QUESTION TWO
Discuss the implications of cigarette smoking and alcohol intake on the health of a user. (25marks)
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