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Dcmp 128: Medical Microbiology 11 Question Paper
Dcmp 128: Medical Microbiology 11
Course:Medical Laboratory Sciences
Institution: Kenya Methodist University question papers
Exam Year:2012
KENYA METHODIST UNIVERSITY
END OF 2''ND ''TRIMESTER 2012(DAY) EXAMINATIONS
SCHOOL : MEDICINE & HEALTH SCIENCES
DEPARTMENT : MEDICAL LABORATORY SCIENCES
UNIT CODE : DCMP 128
UNIT TITLE : MEDICAL MICROBIOLOGY 11
TIME : 3HOURS
INSTRUCTIONS: Answer ALL Questions in Section A and B and TWO Questions in Section C
SECTION A (20marks)
QUESTION ONE
The identification of bacteria by serologic tests is based on the presence of specific antigens. Which of the following bacterial components is least likely to contain useful antigens?
A. Ribosomes
B. Cell wall
C. Capsule
D. Flagella
E. Pilli
QUESTION TWO
Each of the following statements concerning gram stain is correct except
A. Escherichia coli stains pink because it has a thin peptidoglycan layer
B. Streptococcus pyogenes stains blue because it has a thick peptidoglycan
layer
C. Mycoplasma pnemoniae is not visible in gram stain because it does not
have a cell wall.
D. Mycobacterium tuberculosis stains blue because it has a thick lipid layer.
E. Staphylococcus stain blue indicating that they are gram positive.
QUESTION THREE
Each of the following organisms is an important cause of urinary tract infections EXCEPT
A. Klebsiella pneumoniae
B. Escherichia coli
C. Bacteroides fragilis
D. Proteus mirabilis
E. Ureaplasma urealyticum
QUESTION FOUR
Each of the following agents is a recognized cause of diarrhea EXCEPT
A. Clostridium perfringens
B. Vibrio cholerae
C. Enterococcus faecalis
D. Escherichia coli
E. Clostridium difficile
QUESTION FIVE
A 30 year old woman has non-bloody diarrhoea for the past 14 hours which one of the following organisms is likely to cause this illness?
A. Streptoccus pyogenes
B. Clostridium difficile
C. Shigella dysenteriae
D. Salmonella enteritidis
E. Enterococcus faecalis
QUESTION SIX
Which of the following bacteria has the lowest 50% infective dose (ID50)?
A. Campylobacter jejuni
B. Salmonella typhi
C. Vibrio cholerae
D. Shigella sonnie
E. Staphylococus aureus
QUESTION SEVEN
Which of the following disease is best diagnosed by serologic means?
A. Pulmonary tuberculosis
B. Gonorrhoea
C. Actinomycosis
D. Q-fever
E. Diptheria
QUESTION EIGHT
Organisms that thrive in elevated carbondioxide are called
A. Microaerophiles
B. Anaerobes
C. Aerotolerant
D. Caprophiles
E. Facultative anaerobes
QUESTION NINE
The outline of cells, nucleus, mitochondria, oil droplets and vacuoles are viewed with
A. Bright field microscope
B. Dark field microscope
C. Fluorescent microscope
D. Ultraviolet microscope
E. Dissecting microscope
QUESTION TEN
All of the following are characteristics of exotoxins, except
A. Tissue specific activity
B. Active even while they are in minute amounts
C. Enzymatic activity
D. Lipopolysaccharides in nature
E. Are produced extracellularly by the pathogens
QUESTION ELEVEN
Escherichia coli is
A. Facultatively anaerobic gram-negative rod
B. Motile by peritrichous
C. Respiratory and fermentative metabolism
D. H2S negative
E. All of the above
QUESTION TWELVE
Which of the following is the confirmative test for staphylococcus aureus?
A. Coagulase test
B. Pigmentation
C. Mannitol fermentation
D. Hernolysis of blood agar
E. Catalase test
QUESTION THIRTEEN
Which of the following fungi is most likely to be found within reticoloendotrelia/cells?
A. Histoplasma capsulatum
B. Sporothrix schenkii
C. Crypotococcus neoformans
D. Candida albicans
E. Coccidioides immitis
QUESTION FOURTEEN
Aspergillosis is recognized in tissue by the presence of
A. Metachromatic granules
B. Pseudohyphae
C. Septate hyphae
D. Budding cells
E. Fungal spores
QUESTION FIFTEEN
Immunocompromised persons do suffer from several fungal diseases. Which of the following is the least frequently associated
A. Cryptococcus neoformans
B. Aspergillus formigatus
C. Malassezia furfur
D. Mucor species
E. Candida albicans
QUESTION SIXTEEN
The following statement is NOT CORRECT concerning candida albicans
A. C.albicans is a budding yeast that forms pseudohyphe when it invades
tissue
B. C. albicans cause thrush
C. C. albicans is capable of causing a systemic disease
D. Impaired cell mediated immunity is an important predisposing factor to disease.
E. C. albicans is transmitted primarily by respiratory aerosol
QUESTION SEVENTEEN
The following diseases are caused by entreroviruses EXCEPT ONE:
A. Pleurodynea
B. Glomerulonephritis
C. Paralysis
D. Meningitis
E. Pericarditis
QUESTION EIGHTEEN
The following statement is INCORRECT regarding viral pathogenesis
A. Viruses spread in the body through different routes e.g. Blood, Saliva.
B. Humoral immunity but not cell mediated immunity acts against viruses.
C. Inclusion bodies produced by viruses can be single or many.
D. Cells usually die in cytocidal infections
E. Several RNA viruses can cause persistent infection.
QUESTION NINETEEN
Which of the following is TRUE concerning HCV and HBV?
A. HBV is dsRNA
B. HCV is ssRNA
C. Both viruses can grow in cell culture
D. HBV has no chronic complication
E. They are both reverse transcribing viruses.
QUESTION TWENTY
The following is NOT CORRECT regard poliovirus
A. Two vaccines are available
B. There is no vaccine for polio
C. Can be isolated from throat swab or stool
D. Sub-clinical infections are common
E. Three serotypes exist.
SECTION B
QUESTION TWENTY ONE
Write short notes on human botulism. (5marks)
QUESTION TWENTY TWO
Describe the pathogenicity of mycobacterium ulcerans. (5marks)
QUESTION TWENTY THREE
Describe the pathogenesis of Helibobacter pylori. (5marks)
QUESTION TWENTY FOUR
List FIVE pathogenic bacteria that can cause urinary tract infections. (5marks)
QUESTION TWENTY FIVE
Outline the clinical features of cytomegalovirus. (5marks)
QUESTION TWENTY SIX
Describe the laboratory diagnosis of histoplasmosis. (5marks)
QUESTION TWENTY SEVEN
Outline the clinical features of Rubella infections. (5marks)
QUESTION TWENTY EIGHT
Discuss viral absorption into susceptible host cells. (5marks)
QUESTION TWENTY NINE
Describe the pathogenesis of Q-fever. (5marks)
QUESTION THIRTY
Summarize the clinical features of ocular infection with Chlamydia. (5marks)
SECTION C – ANSWER TWO QUESTIONS
QUESTION THIRTY ONE
Discuss TWO types of herpes viruses under the following topics. (15marks)
Clinical features
Pathogenesis
diagnosis
QUESTION THIRTY TWO
Give a detailed discussion of Hepatitis C viral infection. (15marks)
QUESTION THREE
Discuss the diagnosis, treatment and prevention of TWO examples of superficial mycoses. (15marks)
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