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Sbt 305: General Genetics Question Paper

Sbt 305: General Genetics

Course:Bachelor Of Science Microbiology And Biotechnology

Institution: University Of Nairobi question papers

Exam Year:2011

UNIVERSITY OF NAIROBI
UNIVERSITY EXAMINATIONS 2011/2012
OPEN AND DISTANCE LEARNING PROGRAMME
THIRD YEAR EXAMNATIONS FOR THE DEGREE OF BACHELOR OF SCIENCE
SBT 305: GENERAL GENETICS
DATE: DECEMBER 8, 2011 TIME: 9.00 AM – 12.00
INSTRUCTIONS: ANSWER ALL QUESTIONS FROM SECTIONA AND TWO SELECTED FROM SECTION B.
SECTION A
SHORT ANSWER QUESTIONS (50 minutes , 3 marks each)
1. Provided evidence that DNA is the genetic material.
2. Distinguish “generalized” from “specialised” transduction.
3. Vestigial winged, purple eyed Drosophila flies were mated with the wild type. The resultant F1 progeny were test crossed and the following progenies obtained.
Red eye, normal wings 290
Purple eye, vestigial wings 282
Red eye, vestigial wings 38
Purple eye, normal wings 32
Use a diagram to represent the cross upto the test cross and deduce the distance between the two genes.
4. In a genetics class of 50 students, 35% were found unable to taste PTC. Assuming 2 alleles T and t, calculate genotype and allelic frequencies.
5. Explain the dark DNA repair mechanism.
6. What is mRNA processing? Explain briefly and give an example.
7. How does body colour confer an advantage to the moth Biston betularia?
8. Explain uniparental inheritance of CO2 sensitivity in Drosophila.
9. How are the following used in genetic engineering?
a. Plasmids
b. Restriction endonucleases
10. Outline the mode of regulation of the lac operon.

SECTION B (20 MARKS)
11. Factors that alter genetic equilibrium.
12. Extra chromosomal genetic systems.
13. Inborn metabolic disorders.
14. Changes in chromosome numbers.

Sbt 305: General Genetics Question Paper

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