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Bch 208:Human Cell Biology Question Paper

Bch 208:Human Cell Biology

Course:Bachelor Of Science In Biochemistry And Molecular Biology

Institution: South Eastern Kenya University question papers

Exam Year:2016

SOUTH EASTERN KENYA UNIVERSITY
UNIVERSITY EXAMINATIONS 2016/2017

FIRST SEMESTER EXAMINATION FOR THE DEGREE OF BACHELOR OF SCIENCE IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

BCH 208:HUMAN CELL BIOLOGY
DATE: 16TH, DECEMBER, 2016
TIME:1.30-3.30PM

INSTRUCTIONS TO CANDIDATES.
a)Answer ALL the questions in section A
b)Answer any TWO questions in section B
c)Illustrate your answers with well labeled diagrams where appropriate.

SECTION A(30 Marks)
1)Briefly describe the central dogma of molecular biology. (4 marks)
2)AT rich DNA denatures more easily than DNA strands that are GC rich.Explain. (2 Marks)
3)With respect to DNA molecules distinguish the following terms DNA renaturation/annealing and DNA Denaturation. (4 marks)
4)Briefly describe the Cri du Chat Syndrome in humans. (5 marks)
5)Briefly describe DNA transposons and retrotransposon. (5 marks)
6)Briefly describe the genetic mutation responsible for Fragile X syndrome. (4 marks)
7)Explain the various forms of inversions in respect to chromosomal mutations. (2 marks)
8)Define the following terms with respect to chromosomes;
a)Metacenrtic. (1 mark)
b)Submetacentric. (1 mark)
c)Acrocentric. (1 mark)
d)Telocentric. (1 mark)

SECTION B(40 Marks)
9)Discuss genetic mapping.(20 marks)
10)Discuss the underlying genetic anomalies in Huntington's disease.
(20 marks)
11)Describe the genetic conditions arising from Trisomic chrimosomal abberation. (20 marks)
12)Describe the highly repeated DNA class of DNA sequence. (20 marks)

Bch 208:Human Cell Biology Question Paper

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