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Nurs 116: Medical Biochemistry Ii Question Paper

Nurs 116: Medical Biochemistry Ii 

Course:Bachelor Of Science In Nursing

Institution: Chuka University question papers

Exam Year:2013





CHUKA

UNIVERSITY




UNIVERSITY EXAMINATIONS
FIRST YEAR EXAMINATIONS FOR THE AWARD OF DEGREE OF BACHELOR OF SCIENCE NURSING
NURS 116: MEDICAL BIOCHEMISTRY II
STREAMS: BSC.NURS YIS2 TIME: 2 HOURS
DAY/DATE: THURSDAY 18/4/2013 2.30 PM – 4.30 PM
INSTRUCTIONS:

Answer ALL questions

QUESTION ONE

(a) Define the following terms:

(i) Glucoonegenesis [5 Marks]
(ii) ß – oxidation
(iii) hyper cholesterolimia
(iv) Atherosclerosis
(v) Amino aciduria

(b) Give three advantages of gluconeogenesis [3 Marks]

(c) List two primary functions of the pentose phosphale pathway. [2 Marks]

(d) (i) Define the term ‘uncouplers” [1 Mark]

(ii) Using an example give two types of uncouplers. [2 Marks]

(e) Explain how cholestiasis occurs and how the patient is treated. [4 Marks]
(f) Explain the term “nitrogen balance” [4 Marks]

(g) Give the functions of-:

(i) Serotinin
(ii) Dopamine
(iii) Epine phrine / advanacine. [1.5 Marks]

(h) (i) List three reasons why ammonia is toxic to the central nervous system.
[1.5 Marks]

(ii) Discuss briefly the following stages of protein digestion,

(i) Gastric digestion
(ii) Pancreatic digestion
(iii) Intestinal digestion [6 Marks]

QUESTION TWO

(a) Discuss the first three reactions unique to gluconeogenesis. [6 Marks]

(b) Give four reasons why dietary filter is better than a drug in cholesterol control. [2 Marks]

(c) Discuss briefly the two pathways for the biosynthesis of triacylglycerol. [4 Marks]

(d) List three functions of bile salts. [3 Marks]

(e) Explain briefly the following inborn errors of metabolism of amino acids.

(i) Trysinemia

(ii) Alkaptonuria [4 Marks]

(f) Give two purine bases and two pyrimidine bases. [1 Mark]

QUESTION THREE

(a) Discuss briefly the first three reactions of the kreps cycle. [6 Marks]

(b) List three processes that occur in the presence of uncouplers. [3 Marks]

(c) (i) Discuss ketone body synthesis [3 Marks]

(ii) Give 2 ways in which ketone body synthesis is regulated. [1 Mark]

(iii) List three causes of ketosis. [3 Marks]

(d) Explain the first step of catabolism of most aminoacids. [3 Marks]

(e) Discuss RNA synthesis. [3 Marks]


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