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Nurs 116:Medical Biochemistry Ii Question Paper

Nurs 116:Medical Biochemistry Ii 

Course:Bachelor Of Science(Nursing)

Institution: Chuka University question papers

Exam Year:2012



INSTRUCTIONS:
Answer ALL questions
QUESTION ONE
(a) Define the following terms:
(i) Glucoonegenesis [5 Marks] (ii) ?? – oxidation (iii) hyper cholesterolimia (iv) Atherosclerosis (v) Amino aciduria
(b) Give three advantages of gluconeogenesis [3 Marks]
(c) List two primary functions of the pentose phosphale pathway. [2 Marks]
(d) (i) Define the term „uncouplers” [1 Mark]
(ii) Using an example give two types of uncouplers. [2 Marks]
(e) Explain how cholestiasis occurs and how the patient is treated. [4 Marks]
2
(f) Explain the term “nitrogen balance” [4 Marks]
(g) Give the functions of-:
(i) Serotinin (ii) Dopamine (iii) Epine phrine / advanacine. [1.5 Marks]
(h) (i) List three reasons why ammonia is toxic to the central nervous system. [1.5 Marks]
(ii) Discuss briefly the following stages of protein digestion,
(i) Gastric digestion (ii) Pancreatic digestion (iii) Intestinal digestion [6 Marks]
QUESTION TWO
(a) Discuss the first three reactions unique to gluconeogenesis. [6 Marks]
(b) Give four reasons why dietary filter is better than a drug in cholesterol control. [2 Marks]
(c) Discuss briefly the two pathways for the biosynthesis of triacylglycerol. [4 Marks]
(d) List three functions of bile salts. [3 Marks]
(e) Explain briefly the following inborn errors of metabolism of amino acids.
(i) Trysinemia
(ii) Alkaptonuria [4 Marks]
(f) Give two purine bases and two pyrimidine bases. [1 Mark]
QUESTION THREE
(a) Discuss briefly the first three reactions of the kreps cycle. [6 Marks]
(b) List three processes that occur in the presence of uncouplers. [3 Marks]
(c) (i) Discuss ketone body synthesis [3 Marks]
(ii) Give 2 ways in which ketone body synthesis is regulated. [1 Mark]
(iii) List three causes of ketosis. [3 Marks]
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(d) Explain the first step of catabolism of most aminoacids. [3 Marks]
(e) Discuss RNA synthesis. [3 Marks]
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