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Pml 212: Clinical Physiology Question Paper

Pml 212: Clinical Physiology

Course:Bachelor Of Science In Medical Laboratory Sciences

Institution: Maseno University question papers

Exam Year:2013

MASENO UNIVERSITY

UNIVERSITY EXAMINATIONS 2012/2013

SECOND YEAR FIRST SEMESTER EXAMINATION FOR

THE DEGREE OF BACHELOR OF SCIENCE IN

BIOMEDICAL SCIENCE & TECHNOLOGY WITH

INFORMATION TECHNOLOGY

(MAIN CAMPUS)

PML 212: CLINICAL PHYSIOLOGY

Date: 3rd April, 2013 Time: 8.30—10.30am

INSTRUCTIONS:
Answer ALL questions in Section A.

section B: Answer TWO questions. QUESTION ONE is

COMPULSORY

MASENO UNIVERSITY ISO 9001:2008 CERTIFIED

SECTION A : ANSWER ALL QUESTIONS

I. Explain the terms•, (a) Bulk electro-neutrality (b) Anion gap (4 marks).

2. Describe the following terminologies used in full haemogram

(a) RDW

(b) MCHC (4 marks).

3. Explain the following terms? (4 marks)

(a) Total lung capacity

(b) Inspiratory reserve volume

(c) FEV1

(d) Inspiratory reserve volume

4.Outline the cardiac events represented by these terms in an electrocardiograph?

(a) QRS complex

(b) p Wave

( c) QT interval

(d) T Wave (4 marks )

5.Outline the osmotic fragility behavior of a normal healthy red blood cell as observed in decreasing concentrations of saline (NaCI) solutions? (4 marks)

6.In circulation, red blood cells far outnumber the white blood cells yet in active bone marrow the majority of hemopoietic stem cells are committed towards formation Of white blood cells in the ratio of 3:1. Briefly account for the circulating quantitative disparity in red cells count to White

cells count that contrasts the bone marrow hemopoietic events? (4 marks)

7.Briefly explain the following?

(a) Simple feedback hormonal regulation

(b) Hierarchical feedback hormonal regulation (4 marks)

8. Illustrate components that the functional unit of a cardiac muscle cell, the sarcomere? (4 marks)

9. List the structural components of the glomerular filtration barrier?
(4 marks)

10. List any four hormones of the anterior pituitary gland and one function corresponding to each?

(4 marks)?

SECTION B: ANSWER TWO QUESTIONS. Question ONE IS COMPULSORY.

1. Substance X can be used to rate and renal clearance, While

substance Y can be used to measure the glomerular filtration rate, renal clearance and renal

plasma flow per unit time.

a) Describe glomerular nitration rate (2 ma

b) Describe (2 marks)

c) Describe renal plasma flow t 2 m arks )

d) Explain the properties of substance X and Y that enable them to be used to assess the

specific kidney functional parameters outlined above 14 marks).

e) Describe the rote of Starling's forces in formation of fluid ultrafiltrate in the glomerular capillaries (5 marks).

2. Discuss the phases of the cardiac cycle from the point of the ventricles including the blood volumes handled through one cycle and the associated cardiac events? (15 marks)

3. Discuss the mechanisms of blood coagulation? (15 marks)

Pml 212: Clinical Physiology Question Paper

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