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Mels 229: Pharmacology Question Paper

Mels 229: Pharmacology

Course:Bachelor Of Science In Medical Laboratory Science

Institution: Kisii University question papers

Exam Year:2017

ANSWER ALL QUESTIONS IN SECTION A AND ANY TWO IN SECTION B
SECTION A
1.
Define Bioassays.Mention the indications of Bioassay and explain about types of Bioassay.(10marks)
2.Explain the following with example(5x2=10)
a) Plasma protein binding of drugs
b) Volume of distribution
c) Bioavailability
d) Plasma half life
c) Zero order kinetics

3.
a)What is antagonism ? Explain different types of antagonism with examples.(5marks)
b) Explain the mechanism of action and adverse effects of oral hypoglycemic agents.(5marks)
4.
a)Explain the mechanism of development of resistance to ant-biotic .(5marks)
b) Classify penicillim's and cephalosporin's and explain their mechanisms of action.(5marks)
SECTION B
5.
Explain various routes of drug administration with their advantages and disadvantages.(15marks)
6.
Define hypertension.What are the different types of hypertension? Enumerate anti-hypertensive drugs with examples write the mechanism,adverse effects and uses of any one,class of drug.(15marks)
7.What are anti-inflammatory drugs? Classify them with suitable examples.Discuss the pharmacological action,adverse effects and therapeutic uses of aspirin.(15marks)

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