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Pmt 435: Prokaryotic And Eukaryotic Gene Expression Question Paper

Pmt 435: Prokaryotic And Eukaryotic Gene Expression

Course:Bachelor Of Science In Medical Biotechnology

Institution: Maseno University question papers

Exam Year:2016

MASENO UNIVERSITY

UNIVERSITY EXAMINATIONS 2016/2017

FOURTH YEAR FIRST SEMESTER EXAMINATION FOR
DEGREE OF BACHELOR OF SCIENCE IN MEDICAL BIOTECHNOLOGY
WITH INFORMATION TECHNOLOGY

MAIN CAMPUS

PMT 435: PROKARYOTIC AND EUKARYOTIC GENE EXPRESSION

Date: 3rd December, 2016 Time: 12.00-3.00pm

INSTRUCTIONS:
.Answer ALL Questions in Section A and any other TWO in Section B.

MASENO UNIVERSITY ISO 9001:2008 CERTIFIED

SECTION A(40 marks)

1. Describe the process of recombination in eukaryotic cells(5 marks)

2. Transposons are a major source of genetic mutations. Briefly comment(5 marks)

3. Organelle genomes are much smaller and have limited gene contents. Comment(5 marks)

4. Briefly describe the structure and function of spliceosomes(5 marks)

5. Suppressor mutation can lead to a functional phenotype. Briefly describe(5 marks)

6. Briefly discuss five applications of karyotyping(5 marks)

7. Write short notes on tandem repeats(5 marks)

8.B cells generate antibody diversity by alternative mRNA splicing. Describe how this process takes place(5 marks)

SECTION B(30 marks)
10.Describe the various structural organization levels of the DNA molecule in a chromosome(15 marks)

11.Discuss the processes of mRNA translation and regulation in eukaryotes(15 marks)

12.Discuss DNA damage and repair mechanisms(15 marks)

Pmt 435: Prokaryotic And Eukaryotic Gene Expression Question Paper

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