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Nur 113: Medical Biochemistry Question Paper

Nur 113: Medical Biochemistry

Course:Bachelor Of Science Nursing

Institution: Chuka University question papers

Exam Year:2012

1
CHUKA UNIVERSITY
COLLEGE
UNIVERSITY EXAMINATIONS
EXAMINATION FOR THE AWARD OF DEGREE OF
BACHELOR OF SCIENCE (NURSING)
NUR 113: MEDICAL BIOCHEMISTRY
STREAM: BSC (NURSING) TIME: 2 HOURS
DAY/DATE: FRIDAY 14/12/2012 2.30 A.M. – 4.30 P.M
INSTRUCTIONS:
ANSWER ALL QUESTIONS
QUESTION 1
(a) Define the term “medical biochemistry”. [1 Mark]
(b) What is the concentration of the H
+
in a solution of 0.1M
NaOH (KW = 1.0x10
-14
m
2
) [3 Marks]
(c) Define the following terms
(i) Acids
(ii) Bases
(iii) Buffers
(iv) Enzymes
(v) Hydrogen bonds
(vi) Apoenzyme
(vii) Holoenzyme [4 Marks]
2
(d) Calculate the P
H
of a mixture of 0.1M acetic acid and 0.20M sodium acetate. The
Pka of acetic acid is 4.76. [2 Marks]
QUESTION 2
(a) Define the following terms
(i) Free energy
(ii) Standard free energy
(iii) Oxidation
(iv) Reduction [2 Marks]
(b) List three major classes of carbohydrates. [1.5 Marks]
(c) Give 2 functions of bile salts. [1.0 Marks]
(d) Differentiate between:
(i) Aldoses and Ketoses [1 Mark]
(ii) Homopolysaccharide and Heteropolysaccharide [1 Marks]
(e) (i) Explain briefly what are glycosaminoglycans [1/2 Mark]
(ii) Give 3 functions of glycosaminoglycans [3 Marks]
QUESTION 3
(a) Define glycolysis. [1 Mark]
(b) List 2 significances of the glycolytic pathway. [2 Marks]
(c) Explain the following terms:
(i) Proteoglycans
(ii) Gluconeogenesis [2 Marks]
(d) Give 3 advantages of gluconeogenesis. [3 Marks]
(e) Explain briefly 2 general functions of lipids. [2 Marks]
3
QUESTION 4
(a) Briefly discuss lactose intolerance. [5 Marks]
(b) Explain briefly the two mechanisms of absorption of carbohydrates. [4 Marks]
(c) Give and explain briefly the functions of fatty acids. [4 Marks]
(d) Draw the general formula of an a- aminoacid. [3 Marks]
(e) Give 4 levels of protein organisation. [2 Marks]
(f) List two functions of the kidneys. [2 Marks]
QUESTION 5
(a) Briefly explain galactosemia. [5 Marks]
(b) List and explain the reactions of stage1 of the glycolytic pathway. [3 Marks]
(c) Explain briefly five functions of phospholipids. [5 Marks]
(d) Name and explain briefly three lipid storage diseases. [3 Marks]
(e) Discuss the biosynthesis of triacyl glycerols. [4 Marks]
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Nur 113: Medical Biochemistry Question Paper

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