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Pmb 323: Medical Virology Question Paper

Pmb 323: Medical Virology

Course:Bachelor Of Science In Medical Biotechnology

Institution: Maseno University question papers

Exam Year:2016

MASENO UNIVERSITY

UNIVERSITY EXAMINATIONS 2015/2016

THIRD YEAR SECOND SEMESTER EXAMINATIONS FOR THE DEGREE
OF BACHELOR OF SCIENCE IN MEDICAL BIOTECHNOLOGY WITH
INFORMATION TECHNOLOGY

MAIN CAMPUS

PMB 323: MEDICAL VIROLOGY

Date: 18th April, 2016 Time: 11.00-1.00pm

INSTRUCTIONS:
.Answer ALL questions in SECTION A and any TWO in SECTION B.

MASENO UNIVERSITY ISO 9001:2008 CERTIFIED

SECTION A: Answer ALL Questions

Q 1.What do you understand by the term "Viruses" and how do they differ from "Plasmids"? (4 marks)

Q 2.How do positive-stranded RNA viruses differ from negative-stranded RNA viruses in terms of their cellular infectivity (5 marks)

Q 3.How does the paralytic stage of Poliomyelitis arise?(6 marks)

Q 4.For each of the following viruses indicate;

a)Whether it is enveloped or non-enveloped(10 marks)

b)The nature of its nucleic acid(single-stranded, double-stranded, type of nucleic acid and nucleotides) (10 marks)

c)Strategy in the synthesis of its genome(15 marks)

d)Presenting clinical symptoms(10 marks)

e)How it is managed(5 marks)

VIRUSES;
i)Human Influenza virus
ii)Hepatitis B virus
iii)Herpes Simplex Virus type I
iv)Human Immunodeficiency virus
v)Human Papilloma virus

SECTION B: Answer Question 5 and either Question 6 OR Question 7

Q 5.Discuss the mechanisms by which the following drugs when combined achieve optimum anti-virus chemotherapeutic activities and thereby minimize development of resistance(20 marks)

a)Azidothymidine and Dideoxycytidine
b)A Protease Inhibitor

Q 6.Discuss the biochemical basis for the success of anti-herpes drugs like Acyclovir and 5-Methoxymethyl deoxycytidine in treatment of Herpes labialis or Herpes genitalis in human(15 marks)

Q 7.List cancers usually seen in people infected with Human Immunodeficiency Virus-I and briefly explain the mechanism by which they arise.(15 marks)

Pmb 323: Medical Virology Question Paper

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