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Pmt 217:General Pharmacology Question Paper

Pmt 217:General Pharmacology

Course:Bachelor Of Science In Medical Laboratory Sciences

Institution: Maseno University question papers

Exam Year:2015

MASENO UNIVERSITY

UNIVERSITY EXAMINATIONS 2014/2015

SECOND YEAR FIRST SEMESTER EXAMINATIONS FOR THE
DEGREE OF BACHELOR OF SCIENCE IN PHARMACEUTICAL SCIENCES
& BACHELOR OF SCIENCE IN MEDICAL LABORATORY SCIENCES WITH
INFORMATION TECHNOLOGY

(MAIN CAMPUS)

PMT 217: GENERAL PHARMACOLOGY

Date:1st April,2015 Time:11.00-1.00pm

INSTRUCTIONS:
.Answer Question ONE and any other FOUR questions.

MASENO UNIVERSITY ISO 9001:2008 CERTIFIED

Q 1.Briefly explain the following terms as they are used in pharmacology and OR therapeutics

a)Drug antagonism(5 marks)

b)Translocation of drug molecules (5 marks)

c)pH partition and ion trapping (6 marks)

d)Absorption and distribution of drugs (5 marks)

e)Special drug delivery systems (7 marks)

Q 2.Discuss the methods used by the body in the irreversible loss of drug from the body following enteral or parenteral administration of a drug. Give examples where necessary (18 marks)

Q 3.a)Describe the various components of the Autonomic Nervous System(ANS) including the chemical mediators of physiological functions.(9 marks)

b)Using the concept in (a) above explain how drug Prazosin achieves its selectivity of actions as a anti-hypertensive agent (9 marks)

Q 4.Nitric Oxide(NO) was in the early 1990s described by an American magazine as "The Molecule of the year".Discuss its pharmacological effects and its therapeutics uses. What are the clinical conditions in which Nitric Oxide may play a part (18 marks)

Q 5.Using examples where necessary, discuss the pharmacological actions and the common unwanted effects of Non-Steroidal Anti-Inflammatory Drugs(NDAIDs)(18 marks)

Q 6.Discuss the mechanisms of selectivity of actions of the various drugs used in the chemotherapy of infectious diseases.(18 marks )

Pmt 217:General Pharmacology Question Paper

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