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Nurs 115: Medical Physiology Ii Question Paper

Nurs 115: Medical Physiology Ii 

Course:Bachelor Of Science In Nursing

Institution: Chuka University question papers

Exam Year:2013





CHUKA

UNIVERSITY




UNIVERSITY EXAMINATIONS
FIRST YEAR EXAMINATIONS FOR THE AWARD OF DEGREE OF BACHELOR OF SCIENCE NURSING
NURS 115: MEDICAL PHYSIOLOGY II
STREAMS: BSC.NURS YIS2 TIME: 2 HOURS
DAY/DATE: FRIDAY19/4/2013 11.30 AM – 1.30 PM
INSTRUCTIONS:

SECTION A: MULTIPLE CHOICE QUESTIONS (20 MARKS)
ANSWER ALL QUESTIONS.

1. Which of the following is not a function of sertoli cells.
(a) Nourishment of spermatocytes, spermids and sperm.
(b) Controls movement of spermatogenic cells and the release of sperm into the
lumen of the semineferous tubule.
(c) Produce fluid for spam transport.
(d) They secrete the male hormone testosterone.

2. Concerning the electric signals at the neurons, which of the following statement is not true?
(a) A resting membrane potential exists across the plasma membrane of excitable
cells that are unstimulated.
(b) According to all-or-none principle, if a stimulus is strong enough to generate an
action potential, the impulse generated is of a constant size.
(c) The amplitude of a graded potential does not vary irrespective of the strength of
the stimulus.
(d) During the absolute refractory period, another impulse cannot be generated at all.


3. During muscle contraction, all of the following events occur except;
(a) Cross-bridges are formed when the energized myosin head attaches to actin’s myosin binding site.
(b) ATP hydrolysis
(c) Calcium ions (ca2+) released from the sarcoplasmic reticulum initially binds to
tropomyosin.
(d) Calcium concentration in the cytosol increases.

4. Which of the following statements is false concerning the cerebro spinal fluid. (CSF)?
(a) CSF is formed in the choroid plexuses in the walls of the ventricles.
(b) The pressure of CSF varies depending on the rate of cerebral metabolism
(c) CSF provides an optimal chemical environment for accurate neuronal signaling.
(d) CSF allows exchange of nutrients and waste products between the blood and the
nervous tissue.

5. Based on the neurotransmitter they produce and release, autonomic neurons are classified as either cholinergic or adrenergic. Which of the following is not a cholinergic neuron?
(a) All sympathetic and parasympathetic pre-ganglionic neurons.
(b) Sympathetic postganglionic neurons that innervate most sweat glands.
(c) Most sympathetic postganglionic neurons
(d) All parasympathetic postganglionic neurons.

6. The adrenal cortex secretes steroid hormones that are essential for life . which of the following statements is true concerning the adrenal cortex?
(a) The cells of zona glomerulosa secrete glucocorticoids.
(b) The cells of zona fasciculate secrete mineralocorticoids.
(c) The cells of zona reticular is secrete androgens.
(d) The sympathetic nervous system is responsible for regulating adrenocortical
secretions.

7. The high glomemlar filtration rate in the human kidney is the result of the following factors except;
(a) Capillary hydrostatic pressure is higher in the glomerulus than in other capillaries
(b) The total glomerulous filtration barriers is larger and porous than other capillary
beds.
(c) The colloid osmotic pressure is much higher in the glomerulus compared to other
capillary beds.
(d) The high rate of renal blood flow helps sustain a high GFR by limiting rise in
colloid osmotic pressure.

8. During fertilization, a very large number of sperm is required for successful fertilization because only a tiny fraction ever reaches the secondary oocyte. Which of the following statements is not true concerning the seminal fluid?

(a) Seminal fluid has a slightly acidic pH of 6.2 – 6.7.
(b) The prostatic secretion gives semen a milky appearance.
(c) Seminal fulid provides sperms with transportation medium.
(d) The volume of semen in a typical ejaculation is about 50-150 million sperms per
mL.

9. Concerning the physiology of the autonomic nervous system, which of the following statements is wrong?
(a) The effects of parasympathetic stimulation are longer lasting and more
widespread than those of sympathetic stimulation.
(b) The sympathetic division favors body function that can support vigorous physical
activity and rapid production of ATP.
(c) The parasympathetic division regulates activities that conserve and restore body
energy.
(d) Most postganglionic neurons of the sympathetic division release norepinephrine
while postganlianic neurous of the parasympathetic division release acetylcholine.

10. During the menstrual phase of the female reproductive cycle, the following events occurs except:
(a) In the ovaries, several primordial follicles develop into primary follicles and then into secondary follicles, under the influence of FSH.
(b) Menstrual flow from the uterus taken place.
(c) The uterine endometrium thickens.
(d) There is declining levels of progesterone and estrogens.

11. Which of the following statements is not true concerning Neurotransmitters?
(a) Acetylcholine is an excitatory neurotransmitter at some synapses while it is
inhibitory at other synapses.
(b) Norepinephrine, dopamine and epinephrine are categorized chemically as
catecholamine’s.
(c) Gamma amino butyric acid (GABA) and glycine are important excitatory
neurotransmitters.
(d) Brain neurons containing the neurotransmitters dopamine are active during
emotional responses, addictive behaviours and pleasurable experiences.

12. The following statements are true about muscle proteins except;
(a) The two structural proteins in muscle are myosin and actin.
(b) Tropomyosin and troponin are the key regulatory proteins in muscle.
(c) Contractile proteins generate force during contraction, while regulatory proteins
help switch contraction on and off.
(d) Structural proteins give the myofibril elasticity and extensibility, and link the
myofibrils to the sarcolemma and extracellular matrix.

13. Which of the following is the most abundant nitrogenous waste in blood?
(a) Uric acid
(b) Urea
(c) Ammonia
(d) Creatinine
14. Concerning reabsorption and secretion at the proximal convoluted tubule (PCT), the following statements are true except;
(a) The proximal convoluted tubule reabsorbs all filtered glucose and aminoacids.
(b) The Na+/K+-ATpase pump is located along the apical membrane of the proximal
tubule cells.
(c) The proximal tubular fluid is essentially isosmotic to blood.
(d) The active Na+/K+-ATpase pump is essential for sodium reabsorption, which
serves as the major driving force for reabsortption of solute and water in the proximal tubule.

15. Which of the following statements regarding hormone release from the anterior pituitary is untrue?
(a) Somatotrophs are the most numerous cells in the anterior pituitary.
(b) There is no gonadotropin – inhibiting hormone
(c) Prolactin (PRL) SOLELY initiates and maintains milk secretion by the mammary
glands.
(d) Gonatotrophs secrete two gonadotropins, follicle-stimulating hormone (FSH) and
luteinizing hormone (LH).

16. The following statements are true concerning the loop of Henle except;
(a) The descending limb of the loop of Henle is highly permeable to water.
(b) The thick ascending limb is a water – impermeable segment.
(c) The thick ascending limb has abundant water channels.
(d) The loops of henle are countercurrent multipliers; they set up an osmotic gradient
in the kidney medulla.

17. In the neurons, saltatory conduction occurs only;
(a) At chemical synapses
(b) In the initial segment of an axon
(c) In myelinated nerve fibres
(d) In unmyelinated nerve fibres.

18. To make a muscle contract more strongly, then nervous system activates more motor units, by a process referred to as;
(a) Recruitment
(b) Summation
(c) Twitch
(d) Treppe

19. Which of the following is the most potent stimulus for hypothalamic production of ` Antidiuretic hormone (ADH)?
(a) High plasma osmolarity
(b) Low plasma osmolarity
(c) Low plasma potassium level
(d) Increase in blood pressure.

20. All of the following are actions of Parathyroid hormone (PTH) except;

(a) Parathyroid hormones promote resorption of bone which release Ca2+ into
blood.
(b) Parathyroid hormone stimulates the kidneys to synthesize calcitriol, the active form of vitamin D.
(c) Parathyroid hormone slows the loss of Ca2+ in urine.
(d) High level of Ca2+ in blood stimulates release of more parathyroid hormone form
the parathyroid gland.

SECTION B: SHORT – ANSWER QUESTIONS (30 MARKS)

ANSWER ALL QUESTIONS

1. Describe the physiological effects of glucocorticoids. [5 Marks]

2. Briefly explain the events that take place during the process of signal transduction at a chemical synapse. [5 Marks]

3. (a) List the type of hormone secreting cells in the islets of langahans and the specific
hormone produced by each. [2 Marks]

(b) Explain the principal actions of insulin in the following organs:
(i) Skeletal muscle [1 Mark]
(ii) Livel [1 Mark]
(iii) Adipose tissue. [1 Mark]

4. Describe the properties of the muscular tissue that enable it to function and contribute to homeostasis. [4 Marks]

5. (a) List 4 hormones secreted by the placenta. [2 Marks]

(b) Explain the role of progesterone in the maintenance of pregnancy [3 Marks]

6. (a) Describe the main contents of the cerebrospinal fluid. [3 Marks]

(b) State the contribution of the CSF in the maintenance of homeostasis? [3 Marks]

SECTION C: LONG – ANSWER QUESTION (20 MARKS)

1. (a) Briefly, describe the glomenular filtration membrane. [3 Marks]





(b) Glomenular filtration rate (GFR) is kept nearly constant despite the day-to-day
changes in the mean arterial blood pressure. Briefly explain how the following mechanisms control the GFR.

(i) Renal auto regulation [3 Marks]

(ii) Hormonal regulation [3 Marks]
(iii) Neural regulation [3 Marks]

(c) What are the main functions of the kidneys in the maintenance of homeostasis? [8 Marks]

2. The effects of thyroid hormones are experienced throughout the body since most body cells have receptors for thyroid hormones.
(a) List all the hormones that are synthesized and released from the thyroid gland. [3 Marks]

(b) Describe the physiological effects of the thyroid hormones. [9 Marks]

(c) The endocrine and nervous systems act together to coordinate functions of all
body systems. Briefly, compare the control by the two systems in the maintenance of homeostasis. [8 Marks]

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